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4 days ago · Flat, light brown spots on the skin, known as cafe au lait spots. These harmless spots are common in many people. But having more than six cafe au lait spots suggests NF1. They often are present at birth or appear during the first years of life. After childhood, new spots stop appearing. Freckling in the armpits or groin area.
Café-au-lait spots are light brown in color, like the color of “coffee with milk.” About 10% to 25% of the general population has café-au-lait spots; NF1 is suspected when a person has 6 or more. People affected by NF1 also tend to develop varying numbers of neurofibromas, meaning benign (noncancerous) tumors on the covering of the nerves.
Café-au-lait spots are most common on the chest, back, pelvis, elbows and knees. These spots may exist at birth or appear during infancy. Between ages 10 and 15, flesh-colored growths of different sizes and shapes may begin to appear on the skin. There may be fewer than 10 of these growths or thousands of them.
Multiple (more than six) café-au-lait spots can be a sign of an underlying genetic condition including: Neurofibromatosis type 1 (NF1). McCune-Albright syndrome. Noonan syndrome. Watson syndrome. If you notice your child has more than six café-au-lait spots on their body, visit your child’s healthcare provider.
Oct 2, 1998 · Neurofibromatosis 1 (NF1) is a multisystem disorder characterized by multiple café au lait macules, intertriginous freckling, multiple cutaneous neurofibromas, and learning disability or behavior problems. About half of people with NF1 have plexiform neurofibromas, but most are internal and not suspected clinically.
The most common symptom of NF1 is multiple café au lait spots. Symptoms can also affect your eyes and bones, too. You might hear your healthcare provider refer to NF1 as Von Recklinghausen disease. How common is neurofibromatosis type 1? Neurofibromatosis type 1 is the most common form of neurofibromatosis.
The most common symptom of NF1 is the appearance of painless, coffee-coloured patches on the skin, called café au lait spots. However, not everyone with café au lait spots has NF1. The spots can be present at birth or develop by the time a child is 3 years old.
