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  2. ACROBiosystems offer S & N Pros for R&D on human-infecting coronavirus & specificity test. HCoV-HKU1 & NL63 & 229E & OC43, SARS, MERS, HEK293 S & E.coli expressed

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  2. Common Human Coronaviruses. Common human coronaviruses, including types 229E, NL63, OC43, and HKU1, usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. Most people get infected with one or more of these viruses at some point in their lives.

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  3. Human coronavirus OC43 (HCoV-OC43) is a member of the species Betacoronavirus 1, which infects humans and cattle. The infecting coronavirus is an enveloped, positive-sense, single-stranded RNA virus that enters its host cell by binding to the N-acetyl-9-O-acetylneuraminic acid receptor.

  4. Nov 2, 2023 · What you need to know. One of the ongoing puzzles of the COVID-19 pandemic is understanding the causes and risk factors for Long COVID. A study funded by several NIH institutes found that previous infection with OC43, a coronavirus that causes the common cold, may increase the risk for Long COVID.

  5. May 25, 2022 · Human coronavirus OC43 is a globally circulating common cold virus sustained by recurrent reinfections. How it persists in the population and defies existing herd immunity is unknown. Here we...

  6. Mar 1, 2021 · Specifically, HCoV-229E encodes two accessory proteins 4a and 4b; HCoV-OC43 encodes three accessory proteins ns2a, ns12.9 (a.k.a. ns5a), and protein I (a.k.a. N2 or N internal ORF protein); HCoV-NL63 encodes a single accessory protein 3; and HCoV-HKU1 encodes two accessory proteins: protein 4 and protein I.

    • Ding X. Liu, Jia Q. Liang, To S. Fung
    • 10.1016/B978-0-12-809633-8.21501-X
    • 2021
    • Encyclopedia of Virology. 2021 : 428-440.
  7. Nov 24, 2021 · Since the presentations of HCoVOC43 and severe acute respiratory syndrome coronavirus 2 (SARS‐COV‐2) are believed to resemble a lot, the aim of this study was to evaluate the frequency and characteristics of HCoVOC43 in the current pandemic and the rate of coinfection for the two viruses.

  8. Feb 20, 2023 · Several antiviral candidates for coronavirus infection were identified by using HCo-OC43 to treat endemic coronavirus infections. Since the COVID-19 pandemic, the utility of HCoV-OC43 has been further applied to the discovery of anti-SARS-CoV-2 compounds due to its low-risk potential.

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