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Common Human Coronaviruses. Common human coronaviruses, including types 229E, NL63, OC43, and HKU1, usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. Most people get infected with one or more of these viruses at some point in their lives.
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Human coronavirus OC43 (HCoV-OC43) is a member of the species Betacoronavirus 1, which infects humans and cattle. The infecting coronavirus is an enveloped, positive-sense, single-stranded RNA virus that enters its host cell by binding to the N-acetyl-9-O-acetylneuraminic acid receptor.
Nov 2, 2023 · What you need to know. One of the ongoing puzzles of the COVID-19 pandemic is understanding the causes and risk factors for Long COVID. A study funded by several NIH institutes found that previous infection with OC43, a coronavirus that causes the common cold, may increase the risk for Long COVID.
May 25, 2022 · Human coronavirus OC43 is a globally circulating common cold virus sustained by recurrent reinfections. How it persists in the population and defies existing herd immunity is unknown. Here we...
Mar 1, 2021 · Specifically, HCoV-229E encodes two accessory proteins 4a and 4b; HCoV-OC43 encodes three accessory proteins ns2a, ns12.9 (a.k.a. ns5a), and protein I (a.k.a. N2 or N internal ORF protein); HCoV-NL63 encodes a single accessory protein 3; and HCoV-HKU1 encodes two accessory proteins: protein 4 and protein I.
- Ding X. Liu, Jia Q. Liang, To S. Fung
- 10.1016/B978-0-12-809633-8.21501-X
- 2021
- Encyclopedia of Virology. 2021 : 428-440.
Nov 24, 2021 · Since the presentations of HCoV‐OC43 and severe acute respiratory syndrome coronavirus 2 (SARS‐COV‐2) are believed to resemble a lot, the aim of this study was to evaluate the frequency and characteristics of HCoV‐OC43 in the current pandemic and the rate of coinfection for the two viruses.
Feb 20, 2023 · Several antiviral candidates for coronavirus infection were identified by using HCo-OC43 to treat endemic coronavirus infections. Since the COVID-19 pandemic, the utility of HCoV-OC43 has been further applied to the discovery of anti-SARS-CoV-2 compounds due to its low-risk potential.
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related to: coronavirus oc43ACROBiosystems offer S & N Pros for R&D on human-infecting coronavirus & specificity test. HCoV-HKU1 & NL63 & 229E & OC43, SARS, MERS, HEK293 S & E.coli expressed