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May 12, 2015 · According to a new study published in the journal Diabetes, some people are cursed with slower metabolisms that make it harder to lose those last few pounds. Researchers at the National...
- Managing Editor, Newsroom
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What are thrifty and spendthrift metabolic phenotypes?
What is a thrift phenotype?
What is the thrifty gene hypothesis?
Can FGF21 help a metabolically thrifty person lose weight?
Energy conservation directed at accelerating body fat recovery (or catch-up fat) contributes to obesity relapse after slimming and to excess fat gain during catch-up growth after malnutrition. To investigate the mechanisms underlying such thrifty metabolism for catch-up fat, we tested whether during ….
- Serge Summermatter, Davide Mainieri, A. P. Russell, Josiane Seydoux, Jean-Pierre Montani, Anthony J....
- 2008
Sep 15, 2009 · Single nucleotide polymorphisms of thrifty genes for energy metabolism: evolutionary origins and prospects for intervention to prevent obesity-related diseases.
- J C K Wells
- J.Wells@ich.ucl.ac.uk
- 2009
Definition of thrifty and spendthrift metabolic phenotypes. Human metabolic phenotypes can be revealed by measuring the short-term (24 hours) response to fasting and overfeeding (especially, low-protein overfeeding) from conditions of energy balance.
- Paolo Piaggi
- 10.1002/oby.22456
- 2019
- 2019/05
Jan 31, 2019 · A thrifty phenotype is thus prone to less weight loss during underfeeding but greater weight gain with overfeeding. This phenotype is considered metabolically efficient and presumably engenders a risk of obesity.
Evolution has molded metabolic thrift within humans, a genetic heritage that, when thrust into our modern “obesogenic” environment, creates the current obesity crisis.
The thrifty gene hypothesis, or Gianfranco's hypothesis [citation needed] is an attempt by geneticist James V. Neel to explain why certain populations and subpopulations in the modern day are prone to diabetes mellitus type 2. He proposed the hypothesis in 1962 to resolve a fundamental problem: diabetes is clearly a very harmful medical ...
