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Jan 11, 2024 · The HES criteria are as follows: Hypereosinophilia is characterized by >1.5 x 10 9 eosinophils on CBC on 2 examinations >1 month apart. The percentage of eosinophils in the bone marrow (BM) section must exceed 20% of all nucleated cells.
- Elizabeth S. Mikhail, Abhijeet Ghatol
- 2024/01/11
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What are the HeS criteria for hypereosinophilia?
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Dec 9, 2022 · Given the broad differential diagnosis of HES, a comprehensive approach is needed to identify potential secondary (treatable) causes and define end-organ manifestations. Classification by clinical HES subtype is also useful in terms of assessing prognosis and guiding therapy.
Jul 22, 2022 · The hypereosinophilic syndromes (HES) are a group of disorders marked by the sustained overproduction of eosinophils, in which eosinophilic infiltration and mediator release cause damage to multiple organs.
- Overview
- Symptoms
- Causes
- Risk factors
Hypereosinophilic (hy-per-ee-o-SIN-o-phil-ik) syndrome (HES) is a group of blood disorders that occur when you have high numbers of eosinophils — white blood cells that play an important role in your immune system. Over time, the excess eosinophils enter various tissues, eventually damaging your organs.
The most common targets are the skin, lungs, digestive tract, heart, blood and nervous system. Untreated, HES can become life-threatening.
Early symptoms of HES may include fatigue, cough, breathlessness, muscle pain, rash and fever.
Some varieties of hypereosinophilic syndrome tend to run in families. Other types have been associated with certain types of cancers, infections or other health problems.
HES can affect anyone. But it occurs more often in men, usually between the ages of 20 and 50.
Learn about the definition, causes, symptoms, diagnosis, and treatment of hypereosinophilic syndrome, a condition with peripheral blood eosinophilia and organ dysfunction. Find out the differences between clonal and idiopathic subtypes, and the molecular abnormalities involved.
Apr 27, 2022 · Hypereosinophilic syndrome is a disorder of certain types of white blood cells that can cause life-threatening damage to your organs.
Nov 30, 2018 · Hypereosinophilic syndromes (HESs) are a heterogeneous group of rare disorders characterized by peripheral eosinophilia and eosinophilic end organ complications. Conventional therapies, including glucocorticoids and cytotoxic and immunomodulatory agents, have variable efficacy and significant toxicity.
