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A cytotoxic T cell (also known as T C, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8 + T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected by intracellular pathogens (such as viruses or bacteria), or cells that are damaged in other ways.
Jul 26, 2022 · Cytotoxic T-cells are a type of immune cell. They are one of the main types of cells developed in your thymus. Cytotoxic T-cells help fight infections. These cells, along with helper T-cells, are an important part of your adaptive immunity.
Jan 17, 2023 · Learn about the two main types of T-cells: cytotoxic and helper. They help your immune system fight germs and protect you from disease by destroying infected cells and sending signals to other immune cells.
Sep 15, 2020 · Cytotoxic CD8 + T cells are major killers of pathogens and neoplastic cells, with CD4 + T cells playing important roles in the maintenance of the CD8 + response and prevention of exhaustion....
- Hans Raskov, Adile Orhan, Jan Pravsgaard Christensen, Ismail Gögenur
- 2021
Jun 19, 2023 · T cells are developed from bone marrow (BM)-derived thymocyte progenitors in the thymus, and broadly grouped into CD4 + and CD8 + αβ T cells in addition to rear populations of γδ T...
Dec 6, 2022 · How did scientists discover and elucidate the cytotoxic function of T cells in immune defence? This article traces the milestones and discoveries from 1950 to 2022, from the first evidence of cell-mediated immunity to the molecular mechanisms of lysis.
May 9, 2021 · Learn how cytotoxic T cells (or 'killer' T cells) directly attack and destroy infected host cells using cytotoxic granules and cytokines. Find out how they are activated, regulated, and differentiate into memory cells.
