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What causes sepsis in children?
How common is pediatric sepsis?
Is sepsis a leading cause of death in children?
Pediatric sepsis is a common cause of morbidity and mortality in the United States. It accounts for over 75,000 pediatric inpatient admissions annually, is associated with a mortality rate of 5 to 20%, and results in decreased functional status in approximately one-third of survivors. (Ames 2018)
Sepsis can develop from an injury as simple as an infected scrape on the arm, or it can emerge on top of an already life-threatening condition, such as acute appendicitis. “Those who have a weakened immune system, like kids undergoing chemotherapy, can be especially susceptible,” Dr. Kandil says.
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Dec 7, 2020 · Key points. •. Early signs of septic shock include tachycardia and derangements in temperature, mental status and peripheral perfusion. •. In younger children, intraosseous (i.o.) access is often easier and achieved more quickly than i. v. access. •. Broad-spectrum antibiotics should be given within 1 h of presentation. •.
- H D O'Reilly, K Menon
- 10.1016/j.bjae.2020.09.004
- 2021
- BJA Educ. 2021 Feb; 21(2): 51-58.
a. Sepsis is a leading cause of morbidity and mortality. b. As of 2015, the global prevalence of pediatric severe sepsis was 8.2%. c. Sepsis can occur in all ages but is more common in toddlers, i. Median age: three years. d. Most common sites of infection leading to sepsis: i. Respiratory tract ii. Bloodstream.
Jul 3, 2020 · In 1 US multicenter study, the most common pathogens affecting previously healthy children were Staphylococcus aureus (9.4%), streptococcal species (7.9%), and Escherichia coli (7.1%), whereas the most common pathogens in children with chronic diseases were S. aureus (11%), Candida (9.8%), and Pseudomonas (8.1%). 12 Similar patterns have been ...
- Andrea T. Cruz, Roni D. Lane, Fran Balamuth, Paul L. Aronson, David W. Ashby, Mark I. Neuman, Ellie ...
- 10.1002/emp2.12173
- 2020
- 2020/10
Nov 23, 2021 · For the purposes of this article, septic shock in children is defined as severe infection leading to cardiovascular dysfunction (including hypotension, need for treatment with a vasoactive medication, or impaired perfusion) and ‘sepsis-associated organ dysfunction’ in children is defined as severe infection leading to cardiovascular and/or non-c...
Mar 27, 2024 · Globally, sepsis is the leading cause of death of children, taking nearly 3.4 million lives each year. Approximately 85% of pediatric sepsis deaths occur in children under age 5. Many children who survive sepsis are left with long-term problems.
