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  1. Sep 2, 2012 · Severe sepsis is sepsis (known or suspected infection with systemic manifestations of sepsis) along with sepsis-related tissue hypoperfusion or organ dysfunction. Organ dysfunction or tissue hypoperfusion are defined by the Surviving Sepsis Campaign as any of the below signs or findings:

  2. Severe sepsis occurs when one or more of your bodys organs is damaged from this inflammatory response. Any organ can be affected, your heart, brain, kidneys, lungs, and/or liver. The symptoms you can experience are based on which organ or organs that are affected.

  3. Feb 10, 2023 · Sepsis is a serious condition in which the body responds improperly to an infection. The infection-fighting processes turn on the body, causing the organs to work poorly. Sepsis may progress to septic shock. This is a dramatic drop in blood pressure that can damage the lungs, kidneys, liver and other organs.

  4. Jan 19, 2023 · Overview. What is sepsis? Sepsis is a life-threatening medical emergency caused by your bodys overwhelming response to an infection. Without urgent treatment, it can lead to tissue damage, organ failure and death. Sepsis definition. Sepsis is your bodys extreme reaction to an infection.

  5. May 3, 2024 · Sepsis is a life-threatening condition that happens when the bodys immune system has an extreme response to an infection, causing organ dysfunction (4). The body’s reaction causes damage to its own tissues and organs and it can lead to shock, multiple organ failure and sometimes death, especially if not recognized early and treated promptly.

  6. Nov 1, 2014 · Severe sepsis has been defined as sepsis plus evidence of organ dysfunction (eg, hypotension, oliguria, and metabolic acidosis), and septic shock has been defined as sepsis with persistent signs of hypotension despite fluid resuscitation. 1. , 2.

  7. Apr 1, 2020 · The guidelines define septic shock as sepsis with circulatory, cellular, and metabolic dysfunction that is associated with a higher risk of mortality; the presence of hypotension is no longer...

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