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Sep 13, 2021 · Synovial sarcoma is a malignant soft tissue tumor of uncertain histogenesis with variable epithelial differentiation.
Jan 12, 2023 · Definition / general. Malignant mesenchymal tumor of uncertain lineage that most often presents in the extremities of young adults. While synovial sarcoma occurs in the pleuropulmonary parenchyma with some frequency, it is very rare in the mediastinum ( Mod Pathol 2007;20:760 )
May 19, 2021 · Synovial sarcomas (SS) represent a unique subset of soft tissue sarcomas (STS) and account for 5–10% of all STS. Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation.
May 6, 2023 · Synovial sarcoma (SS) is a mesenchymal tumor with partial epithelial differentiation. It is commonly seen in older children and younger adults. The presence of t (X;18) (p11.2;q11.2) is a pathognomonic feature of synovial sarcoma.
Synovial Sarcoma is a malignant, soft tissue sarcoma caused by a t (X;18) chromosomal translocation mutation most commonly found near joints, but rarely within the joint. The condition usually presents in patients between 15 and 40 years old with a growing mass in proximity to a joint.
Aug 23, 2023 · Synovial sarcoma (SS) is a rare and malignant tumor of the connective tissues that presents challenges in diagnosis and treatment. 1,2 This article describes the epidemiology, clinical and genomic characteristics of SS, and the patient pathway from diagnosis to treatment.
Oct 11, 2022 · Synovial sarcoma can occur in any part of the body, including sites such as the lungs, heart, kidneys, prostate, gastrointestinal tract, pleura and larynx; detection of the SS18::SSX translocation or the chimeric protein is believed to be specific for synovial sarcoma at all sites, irrespective of the tissue
Synovial sarcoma (SS) is a malignant mesenchymal neoplasm with variable epithelial differentiation, with a propensity to occur in young adults and which can arise at almost any site. It is generally viewed and treated as a high-grade sarcoma.
Dec 8, 2017 · Synovial sarcoma (SS) is a rare sarcoma driven by a translocation between SS18 and SSX 1, 2, or 4. With approximately 800 to 1,000 cases a year in the United States, it most commonly affects young adults between the ages of 15 and 30 years.
May 19, 2021 · Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation. Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t (X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes.
