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   What is factor V Leiden?

   • Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. Most people with factor V Leiden never develop abnormal clots.

   Factor V Leiden - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/factor-v-leiden/symptoms-causes/syc-20372423

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   What is a factor V Leiden mutation?

   • People with factor V Leiden have a mutation in their coagulation factor V ( F5) gene. Your F5 gene controls the production of a protein called factor V, which helps your blood clot when needed (such as after an injury). The factor V Leiden mutation changes this protein’s structure.

   Factor V Leiden: Symptoms, Causes & Treatment - Cleveland Clinic

   my.clevelandclinic.org/health/diseases/17896-factor-v-leiden

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   Can factor V Leiden be inherited?

   • A family history of factor V Leiden increases your risk of inheriting the disorder. The disorder is most common in people who are white and of European descent. People who have inherited factor V Leiden from only one parent have a 5 percent chance of developing an abnormal blood clot by age 65. Factors that increase this risk include:

   Factor V Leiden - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/factor-v-leiden/symptoms-causes/syc-20372423

   See all results for this question

2. www.mayoclinic.org › diseases-conditions › factor-vFactor V Leiden - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › factor-v

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   Aug 23, 2022 · Overview. Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. Most people with factor V Leiden never develop abnormal clots.

3. my.clevelandclinic.org › health › diseasesFactor V Leiden: Symptoms, Causes & Treatment - Cleveland Clinic

   my.clevelandclinic.org › health › diseases

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   Oct 4, 2022 · Factor V Leiden is an inherited blood clotting disorder that raises your risk of deep vein thrombosis or a pulmonary embolism. A mutation in your F5 gene causes this disorder, which follows an autosomal dominant inheritance pattern. Most people with this disorder never develop a blood clot.

4. en.wikipedia.org › wiki › Factor_V_LeidenFactor V Leiden - Wikipedia

   en.wikipedia.org › wiki › Factor_V_Leiden

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   Factor V Leiden is the most common hereditary hypercoagulability (prone to clotting) disorder amongst ethnic Europeans. It is named after the Dutch city of Leiden, where it was first identified in 1994 by Rogier Maria Bertina under the direction of (and in the laboratory of) Pieter Hendrick Reitsma.

5. www.ncbi.nlm.nih.gov › books › NBK534802Factor V Leiden Mutation - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK534802

   Apr 8, 2023 · Factor V Leiden (FVL) is a point mutation of factor V resulting in an elimination of the cleavage site in factor V and factor Va. This genetic defect increases the risk of thrombosis, especially in homozygous or pseudo-homozygous FVL-mutated individuals.

   • Author: Sara A. Albagoush, Supriya Koya, Rebanta K. Chakraborty, Amy E. Schmidt
   • Published: 2023/04/08

   • Publish Year: 2021

6. www.webmd.com › dvt › factor-v-leidenFactor V Leiden: Symptoms, Cause, Diagnosis, and Treatment

   www.webmd.com › dvt › factor-v-leiden

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   Factor V Leiden (FVL) is a change in your genes that affects one of the clotting factors in your blood and keeps your body's blood -clotting process from working right. It can cause a disorder...

7. bloodclot.org › factor-v-leidenFactor V Leiden - American Blood Clot Association

   bloodclot.org › factor-v-leiden

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   Factor V Leiden (also known as factor 5) is a blood clotting disorder that affects millions of people across the globe. Many people who have the disorder don’t even know they have it, making it a mysterious and potentially dangerous condition.