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  1. Paget's disease of bone (commonly known as Paget's disease or, historically, osteitis deformans) is a condition involving cellular remodeling and deformity of one or more bones.

  2. Jan 11, 2023 · Paget's (PAJ-its) disease of bone interferes with your body's normal recycling process, in which new bone tissue gradually replaces old bone tissue. Over time, bones can become fragile and misshapen. The pelvis, skull, spine and legs are most commonly affected.

  3. Paget's disease of bone is a chronic disease of the skeleton. In healthy bone, a process called remodeling removes old pieces of bone and replaces them with new bone. Paget’s disease causes this process to shift out of balance, resulting in new bone that is weak and brittle.

  4. Oct 12, 2021 · Paget’s disease of the bone is a rare chronic bone disorder in which there's excessive and disordered bone turnover with both excessive resorption and formation. This is the process by your body breaks down old bone and creates new bone.

  5. Jan 11, 2023 · Paget's disease of bone puts you at high risk of bone fractures. Ask your doctor for advice on preventing falls. He or she may recommend that you use a cane or a walker.

  6. Paget’s disease of bone is a chronic (long-lasting) disorder that causes bones to grow larger and become weaker than normal. The disease usually affects just one or a few bones. The bones most commonly affected by Paget’s disease include: Pelvis. Skull. Spine. Femur and tibia (leg bones).

  7. Paget disease of the bone is a chronic bone disorder. It causes bones to become enlarged and deformed. Bone may become dense, but fragile, because of excessive breakdown and deformation of bone. The disease is the most common bone disorder after osteoporosis in adults older than age 50.

  8. Paget disease of bone is a chronic disorder of the skeleton in which areas of bone undergo abnormal turnover, resulting in areas of enlarged and softened bone. The breakdown and formation of bone increase, resulting in bones that are thicker, but weaker, than normal.

  9. Paget’s disease of bone is a chronic (long-lasting) disorder that causes bones to grow larger and become weaker than normal. With treatment, many people can manage their symptoms, improve pain, and control the effects of the disease.

  10. Paget's disease of bone disrupts the normal cycle of bone renewal, causing bones to become weakened and possibly deformed. It's a fairly common condition in the UK, particularly in older people. It's rare in people under 50 years of age.

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