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Apr 5, 2015 · Ehrlichiosis and anaplasmosis; By Johan S. Bakken, St. Luke’s Hospital, J. Stephen Dumler, University of Maryland School of Medicine Edited by David Schlossberg, Temple University, Philadelphia; Book: Clinical Infectious Disease; Online publication: 05 April 2015; Chapter DOI: https://doi.org/10.1017/CBO9781139855952.193
- Johan S. Bakken, J. Stephen Dumler
- 2004
OVERVIEW. Human ehrlichiosis and anaplasmosis are acute febrile tick-borne diseases caused by various members from the genera Ehrlichia and Anaplasma (Anaplasmataceae).
- Nahed Ismail, Karen C. Bloch, Jere W. McBride
- 10.1016/j.cll.2009.10.004
- 2010
- 2010/03
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October 2021. Cite. Permissions. Share. Abstract. This chapter considers ehrlichiosis as the collective name for infections caused by obligate intracellular gram-negative bacteria belonging to the genera Ehrlichia, Anaplasma, and Neoehrlichia, family Anaplasmataceae.
- Abstract
- Human Infections Caused by Anaplasmataceae Members
- Epidemiology and Ecology
- Clinical and Laboratory Findings
- Diagnosis
- Treatment
- Acknowledgments
"Ehrlichiosis" is a generic name for infections caused by obligate intracellular bacteria in the family Anaplasmataceae, chiefly in the genera Ehrlichia and Anaplasma. Human infections with organisms in this family were first recognized in 1953, with a species now classified as Neorickettsia sennetsu; in 1986, with an Ehrlichia species; and in 1990...
Although 5 Anaplasmataceae members, including A. phagocytophilum, E. chaffeensis, E. ewingii, Ehrlichia canis, and N. sennetsu, infect humans, only the former 3 species are sufficiently investigated. Circulating leukocytes are their targets, and the corresponding diseases are often named according to the infected leukocyte appended by the bacterial...
The agents of human ehrlichiosis are tickborne, and most infections occur during May through August. These infections are now reportable in the United States, and passively collected data provide some measure of their incidence and prevalence . In 2005, more cases of ehrlichiosis were reported than ever before (figure 1), including 471 cases of HME...
HME and HGA are caused by distinct but related bacterial species that propagate in different host cells that are then altered in different ways [1, 6]. Paradoxically, all forms of human ehrlichiosis share many clinical and laboratory manifestations, including fever, headache, myalgia and malaise, thrombocytopenia, leukopenia, and indices of hepatic...
Because human ehrlichiosis can be rapidly progressive and fatal, doxycycline treatment should be initiated promptly once an empirical clinical diagnosis has been rendered, even in the absence of a confirmatory laboratory test. There are several approaches to laboratory confirmation of ehrlichiosis that should be applied at different intervals after...
Although no clinical trials have been conducted, empirical data show that all forms of ehrlichiosis respond to tetracyclines . Currently recommended regimens are shown in table 4. Response is generally very rapid, with improvement evident within 24–48 h, although this can be prolonged in those for whom a significant treatment delay has occurred. Do...
Personal note from J.S.D.: This article is dedicated to the memory of Dr. Theodore E. Woodward, who was Professor Emeritus of Medicine during my tenure as a medical student at the University of Maryland School of Medicine, Baltimore. My interactions with him at this time were instrumental in focusing me toward an academic career in medicine and ric...
- J. Stephen Dumler, John E. Madigan, Nicola Pusterla, Johan S. Bakken, Johan S. Bakken
- 2007
169 - Ehrlichiosis and Anaplasmosis. from Part XXI - Specific Organisms – Rickettsia, Ehrlichia, and Anaplasma. Published online by Cambridge University Press: 05 March 2013. By. Johan S. Bakken and. J. Stephen Dumler. Edited by. David Schlossberg. Chapter. Get access. Cite. Summary.
Ehrlichia, Anaplasma, and Related Infections (Human Ehrlichiosis, Anaplasmosis, and Related Infections Attributable to Bacteria in the Family Anaplasmataceae) | Red Book: 2021–2024 Report of the Committee on Infectious Diseases | Red Book Online | American Academy of Pediatrics. ‹ Prev. Next ›. Book Chapter.
Download chapter PDF. Ehrlichiosis and Anaplasmosis. Introduction. The ehrlichioses are infections of white blood cells that affect various mammals [ 1 ]. Human ehrlichioses represent a group of clinically similar, yet epidemiologically and etiologically diverse, illnesses [ 2, 3 ].
