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  1. Therefore this review will focus on fever as an important variable to be considered in infectious diseases research, focusing especially on studies that reported how pyrexia can affect on the one hand the host immune response , and on the other hand the pathogen response.

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  2. Sep 4, 2023 · Show details. Physiology, Fever. Swetha Balli; Karlie R. Shumway; Shweta Sharan. Author Information and Affiliations. Last Update: September 4, 2023. Go to: Introduction. Fever, or pyrexia, is the elevation of an individual's core body temperature above a 'set-point' regulated by the body's thermoregulatory center in the hypothalamus.

    • 2022/09/11
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  4. Jul 14, 2016 · Fever is a ubiquitous component of inflammation across the animal kingdom, and enhances the host response. A large number of both the cell-derived and plasma-derived inflammatory mediators are pyrogenic; fever associated with inflammation is probably mediated in a similar way to sepsis as described above.

    • Edward James Walter, Sameer Hanna-Jumma, Mike Carraretto, Lui Forni
    • 10.1186/s13054-016-1375-5
    • 2016
    • Crit Care. 2016; 20: 200.
  5. Ewa Grodzinsky, Märta Sund Levander. Approaches the topic of fever in a uniquely broad manner, touching on topics such as measurement accuracy. Provides a review of the latest research on fever and body temperature. Includes hypothetical scenarios of clinical practice to aid in learning and encourage reflection. 17k Accesses. 13 Citations.

  6. Nov 1, 2016 · Feverdefined as ‘a state of elevated core temperature which is often, but not necessarily, part of the defensive responses of a multicellular organism (the host) to the invasion of live (microorganisms) or inanimate matter recognized as pathogenic or alien to the host’.

  7. Nov 20, 2021 · 1 Introduction. Pyrexia (fever) refers to an abnormal increase in temperature occurring under central nervous system control as a component of a co-ordinated biological response. The average normal temperature is usually quoted as 37 °C (98.6 °F) [ 1, 2 ], a value arrived at following research conducted in the 1800s.

  8. A systematic review with meta-analyses and trial sequential analyses found that fever therapy does not seem to afect the risk of death and serious adverse events Insuficient evidence was found to confirm or reject the hypothesis that fever therapy influences quality of life or the risk of non-serious adverse events.

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