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  1. Our 12 unique itineraries provide guests more ways to explore the Mississippi than any other cruise line, while the sophisticated comfort of our modern riverboats offers the largest staterooms, private balconies, and complimentary excursions at every port. Receive Free Airfare & Savings up to $1,000* on select Lower Mississippi River Cruises.

  2. Enjoy our 23-Day Complete Mississippi River experience from New Orleans to St. Paul. Visit Civil War Landmarks & Southern Plantations on Riverboat Ships.

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  4. Enjoy our 9-day Upper Mississippi River Cruise from St. Louis to St. Paul. Tour Mark Twain's Hometown, Black Hawk State Park & other Historic Landmarks.

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  5. Experience Mississippi River Cruises in New Authentic Paddlewheelers with Top Rated Amenities & Personalized Service on the Best Mississippi River Cruises.

  6. Nov 16, 2023 · Looking for the best Mississippi river cruises? Choose from Viking River Cruises, American Cruise Lines and American Queen Voyages to explore the highlights along the Mighty...

  7. 800-460-4518. Ready to plan your Mississippi River Cruise? Find out how to pack for your river cruise, the best time to cruise the Mississippi River, fun facts, and more.

  8. Apr 5, 2024 · American Cruise Line's nine-day Upper Mississippi river cruise covers much of the same ground, with a few differences. Sailings are available on the 150-passenger paddlewheeler American Heritage as well as on three sleek new 180-guest riverboats, American Melody, American Serenade and American Symphony.

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