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     genetik.nat.fau.de

     • An array of approximately 20 types of soluble proteins, called a complement system, functions to destroy extracellular pathogens. Cells of the liver and macrophages synthesize complement proteins continuously. These proteins are abundant in the blood serum and are capable of responding immediately to infecting microorganisms.
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     11.2C: The Complement System - Biology LibreTexts

2. www.nature.com › articles › cr2009139Complement and its role in innate and adaptive immune ...

   www.nature.com › articles › cr2009139

   Dec 15, 2009 · It is now appreciated that complement is a complex network of plasma and membrane-associated serum proteins which can elicit highly efficient and tightly regulated inflammatory and cytolytic...

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   What is a complement system?

   • See more... The complement system consists of several complement proteins synthesized by the liver’s Kupffer cells and subsequently found in the body’s blood and tissues. The proteins themselves are both zymogens, meaning they are typically inactive, and are meta-stable when activated, meaning they require a cell surface to remain active.

   Biochemistry, Complement - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK544229/

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   How many soluble proteins are in a complement system?

   • An array of approximately 20 types of soluble proteins, called a complement system, functions to destroy extracellular pathogens. Cells of the liver and macrophages synthesize complement proteins continuously. These proteins are abundant in the blood serum and are capable of responding immediately to infecting microorganisms.

   11.2C: The Complement System - Biology LibreTexts

   bio.libretexts.org/Bookshelves/Microbiology/Microbiology_(Boundless)/11:_Immunology/11.02:_The_Innate_Immune_Response/11.2C:_The_Complement_System

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   What does the human complement system do?

   • Nearly a century after the significance of the human complement system was recognized, we have come to realize that its functions extend far beyond the elimination of microbes. Complement acts as a rapid and efficient immune surveillance system that has distinct effects on healthy and altered host cells and foreign intruders.

   Complement: a key system for immune surveillance and ... - Nature

   www.nature.com/articles/ni.1923

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   Is complement a powerful inflammatory-inducing system?

   • Accordingly, since complement is both a potent inflammatory-inducing system as well as critically important for innate immune defenses, we need to have a much better understanding of how the system really works.

   The complement system - PMC - National Center for Biotechnology Inf…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC3097465/

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4. onlinelibrary.wiley.com › doi › 10Complement, complosome, and complotype: A perspective

   onlinelibrary.wiley.com › doi › 10

   Apr 30, 2023 · Intracellular complement activation in CD4 + T cells (and some other cells) occurs through the action of the C3-cleaving protease CTSL. The resulting C3a fragment engages intracellular C3aR (for example, on lysosomes) for effector function.

5. www.nature.com › articles › niComplement: a key system for immune surveillance and ... - Nature

   www.nature.com › articles › ni

   Aug 19, 2010 · Our Review highlights recent and emerging trends that better define complement's role in physiology and pathophysiology.

   • Author: Daniel Ricklin, George Hajishengallis, Kun Yang, John D Lambris

   • Publish Year: 2010

6. www.ncbi.nlm.nih.gov › books › NBK544229Biochemistry, Complement - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK544229

   Aug 28, 2023 · The complement system consists of several complement proteins synthesized by the liver’s Kupffer cells and subsequently found in the body’s blood and tissues.

   • Author: Aida Haddad, Allecia M. Wilson

   • Published: 2023/08/28

7. www.ncbi.nlm.nih.gov › pmc › articlesThe complement system - PMC - National Center for ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 14, 2010 · The complement system consists of a tightly regulated network of proteins that play an important role in host defense and inflammation. Complement activation results in opsonization of pathogens and their removal by phagocytes, as well as cell lysis.

   • Author: J. Vidya Sarma, Peter A. Ward
   • DOI: 10.1007/s00441-010-1034-0

   • Publish Year: 2011
   • Publication: Cell Tissue Res. 2011; 343(1): 227-235.

8. bio.libretexts.org › Bookshelves › Microbiology11.2C: The Complement System - Biology LibreTexts

   bio.libretexts.org › Bookshelves › Microbiology

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   Dec 24, 2022 · In this concept, we will discuss the complement system. An array of approximately 20 types of soluble proteins, called a complement system, functions to destroy extracellular pathogens. Cells of the liver and macrophages synthesize complement proteins continuously.

9. www.cell.com › current-biology › fulltextThe complement system: Current Biology - Cell Press

   www.cell.com › current-biology › fulltext

   The complement system. Introduction. The system of plasma proteins called complement was so-named because it complements the activity of antibody in the lysis of bacteria.