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    Stra·tum cor·ne·um
    /ˌsträdəm ˈkôrnēəm/

    noun

    • 1. the horny outer layer of the skin.
  2. Oct 1, 2012 · The stratum corneum (SC), the skin's outermost layer and interface with the outside world is now well recognized as the barrier that prevents unwanted materials from entering, and excessive loss of water from exiting the body.

    • Gopinathan K. Menon, Gary W. Cleary, Majella E. Lane
    • 2012
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  4. Oct 1, 2012 · The stratum corneum (SC), the skin's outermost layer and interface with the outside world is now well recognized as the barrier that prevents unwanted materials from entering, and excessive loss of water from exiting the body.

    • Gopinathan K. Menon, Gary W. Cleary, Majella E. Lane
    • 2012
  5. Jun 8, 2024 · The stratum corneum has 20 to 30 cell layers and occupies the uppermost epidermal layer. The stratum corneum is composed of keratin and dead keratinocytes (anucleate squamous cells) that form horny scales.

    • Hani Yousef, Mandy Alhajj, Sandeep Sharma
    • 2024/06/08
    • 2019
  6. Dec 1, 2018 · The most superficial layer of the epidermis, the stratum corneum, plays a crucial role in retaining hydration; if its structure or composition is compromised, dry skin may result as a consequence of poor water retention. Dry skin is typically treated with topical application of humectant agents that attract water into the skin.

    • Sam Osseiran, Jomer Dela Cruz, Sinyoung Jeong, Hequn Wang, Christina Fthenakis, Conor L. Evans
    • 10.1364/BOE.9.006425
    • 2018
    • 2018/12/12
  7. The fundamental purpose of the stratum corneum is to prevent external water loss and maintain a homeostatic microenvironment within the epidermis. The stratum corneum defends against pathogen invasion by creating both a physical and chemical shield mainly comprising lipids and AMPs, respectively.

  8. The stratum corneum is the outermost layer of the epidermis, composed mainly of dead keratinized cells. It acts as a barrier to protect underlying tissues from infection, dehydration, and physical harm.

  9. The stratum corneum is the outermost superficial epidermal layer that serves as the first line of defense between the body and the environment, and the lower part of this layer is crucial in preventing the penetration of irritants and allergens (Cork et al., 2006).

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