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  1. Dr. Simon Brenner is a fictional medical doctor from the television series ER. Brenner is an attending physician at the ER, and is also the nephew of Donald Anspaugh. He is portrayed by David Lyons.

  2. Lyons began starring in the NBC medical drama ER as Dr. Simon Brenner, making his first appearance in season 14, episode 14 titled "Owner of a Broken Heart" which aired on 10 April 2008, but he was credited as a special guest star.

    Year
    Title
    Role
    Notes
    2022
    Troppo
    Lou Damford
    Series regular
    2021—2023
    Detective Aames
    Series regular
    2019
    Lloyd
    Series regular
    2018
    Mike Diangelo
    Series regular
    • Anthony Edwards played Dr. Mark Greene for eight seasons before leaving after his character—and this is a spoiler alert for a show that premiered more than 20 years ago—died from a brain tumor.
    • Noah Wyle's Dr. John Carter became the focus of the show when Edwards left, and Wyle stuck around for a few seasons later before departing, only to return more than once up until the end of the series.
    • Julianna Margulies' Carol Hathaway was supposed to die from an overdose in the pilot, but she tested well and Margulies stuck around. She became such a central figure she was offered more than $20 million to stick around—but she exited the series at the end of season six with a surprise appearance by Clooney.
    • Eriq La Salle stuck around Cook County General for eight seasons before exiting. However, his Dr. Peter Benton returned as a special guest in the final season.
  3. David Lyons, born April 16, 1976 in Melbourne, Victoria, Australia, is an actor. He played Dr. Simon Brenner from the fourteenth season to the fifteenth and final season of ER. He had initially appeared as a recurring guest star in the fourteenth season and was promoted to series regular in the...

  4. Dr. Simon Brenner : Encourage them to find new careers. Dr. Gregory Pratt : I don't know where you came from, but this is a teaching hospital.

  5. Dr. Archie Morris : If it's still affecting you, you have to deal with it. Dr. Simon Brenner : I am dealing with it, in my own way.

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  7. May 24, 2019 · An infusion of new doctors – like John Stamos’ Dr. Tony Gates, David Lyons’ Dr. Simon Brenner and Angela Bassett’s Dr. Catherine Banfield – brought renewed life to the show to help it ...

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