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- vWF and factor VIII levels tend to rise during pregnancy, but bleeding complications might occur during delivery. Bleeding may be heavier and last longer after giving birth. Women who have a type of von Willebrand’s disease should consult a hematologist and specialized obstetrician when they become pregnant.
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Does von Willebrand disease affect pregnancy and childbirth?
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What is von Willebrand disease (vWD)?
May 15, 2024 · Key points. With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. Close monitoring throughout pregnancy is important for women with VWD. Women with VWD are at risk for serious bleeding after delivery. Pregnancy and childbirth.
Jun 7, 2022 · Background and Objectives Several reports indicate that women with von Willebrand disease (VWD) are at an increased risk of bleeding and other complications during pregnancy and childbirth. The aim of this study was to investigate the effect of VWD on the course of pregnancy, childbirth, and the postpartum period.
Von Willebrand factor is an acute phase reactant, and plasma levels may be high during stress, in pregnant women, and in newborns after vaginal delivery. The levels may be reduced in hypothyroid patients but return to normal when patients become euthyroid. Von Willebrand factor is a large, multimeric glycoprotein encoded on chromosome 12.
Oct 26, 2021 · Von Willebrand disease is a lifelong bleeding disorder in which your blood doesn't clot properly. People with the disease have low levels of von Willebrand factor, a protein that helps blood clot, or the protein doesn't perform as it should.
Download PDF. H&O How common is von Willebrand disease (VWD)? JJ VWD is the most common inherited bleeding disorder, with an incidence of approximately 1 per 1000 people. It has an autosomal inheritance pattern, so men and women are equally likely to be affected.
May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.
