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May reduce skin cancer risk
- A new study conducted in collaboration between the University of Eastern Finland and Kuopio University Hospital found that taking oral vitamin D supplements may reduce skin cancer risk and cases of melanoma. They found that even moderate vitamin D intake helped lower skin cancer risk.
www.eatingwell.com › article › 8024545Taking a Vitamin D Supplement May Lower Skin Cancer Risk, New ...
People also ask
Is vitamin D a good prognostic factor for skin cancer?
Can a skin cancer patient maintain vitamin D without supplementation?
Does vitamin D lower melanoma skin cancer rates?
Researchers believe most people can absorb enough vitamin D from just your “typical” outdoor comings and goings. But, while absorbing the sun’s rays can have health benefits, it can lead to skin cancer. “On a hot summer day, unprotected skin can be damaged in as little as 15 minutes,” Chon says.
- Overview
- Linking vitamin D supplementation and melanoma risk
- Vitamin D, calcidiol, and cancer
- Vitamin D supplements: An alternative to sun exposure
- How much vitamin D do you need?
•A new cross-sectional study observed that people who regularly took vitamin D supplements were less likely to have melanoma, a form of skin cancer, than those who did not take supplements.
•The researchers’ analysis also determined the risk level for melanoma among vitamin D supplement users was significantly reduced compared to that of non-users.
•Despite the implications, study authors and experts suggest following national guidelines for taking vitamin D supplements and caution that maintaining vitamin D levels by themselves is unlikely to prevent or treat melanoma.
A new study finds that the regular use of vitamin D is associated with lower rates of melanoma skin cancer.
The cross-sectional study was a collaboration between the University of Eastern Finland and Kuopio University Hospital.
The research involved 498 Finnish adults determined by dermatologists to be at high risk of skin cancer, such as melanoma, as well as squamous cell carcinoma and basal cell carcinoma.
Study participants ranged in age from 21 to 79 years old, including 253 males and 245 females. Participants were divided into three groups based on their intake of vitamin D supplements: non-use, occasional use, or regular use.
The researchers were also interested in finding out whether regular use of vitamin D supplements corresponded to higher blood levels of vitamin D, known as serum calcidiol or 25-hydroxy-vitamin D3. This is the “storage form” of vitamin D in the body.
Some research has linked low serum calcidiol with increased cancer risk, while other research has suggested otherwise. Nonetheless, it is a measure often used to determine a person’s vitamin D levels.
After testing serum calcidiol levels in 260 participants, researchers found that regular vitamin D supplementation corresponded with the highest levels of serum calcidiol and non-supplementation with the lowest levels.
Lead study author Dr. Ilkka T. Harvima, professor of dermatology and venereology at the University of Eastern Finland, told Medical News Today, “The issue of vitamin D in the context of skin cancers is interesting, though quite controversial.”
Dr. Arup K. Indra, pharmacy professor at Oregon State University, not involved in the study, suggested that vitamin D may protect against oxidative stress and DNA damage, which are associated with cancer risk.
“[Vitamin D] can also be involved in immune modulation, specifically in directing Treg [regulatory T cells] and Th2 cells in immune surveillance,” Dr. Indra told MNT.
Dr. Kim Margolin, medical director of Saint John’s Cancer Institute Melanoma Program in Santa Monica, CA, not involved in the study, told MNT:
“It’s almost impossible for me to believe that a single nutrient could have a statistically significant and clinically significant impact on the development of a disease that requires so many different inputs.”
In addition, not all experts agree that calcidiol is an effective indicator of vitamin D levels in the body.
It has been clear for some time that exposure to ultraviolet (UV) radiation from the sun, and in particular getting sunburned, is a risk factor for skin cancers.
Dr. Margolin explained that UV radiation is the primary cause of basal cell and squamous cell cancers and one of the major risk factors in melanoma.
“Since natural vitamin D is produced by the skin in response to sunlight, reducing UV exposure to avoid cancer reduces the amount of naturally produced vitamin D in the body, potentially leading to a need for supplementation.”
– Kim Margolin, M.D., FACP, advanced oncology physician
According to Dr. Margolin, a person’s vitamin D status may depend on factors other than UV exposure. These include:
•age
It’s too early to determine whether vitamin D supplementation could reduce melanoma risk in the general population, and more research is still needed.
“Vitamin D supplementation alone is unlikely an effective medication to treat metastatic melanoma,” Dr. Harvima said.
“This is important to note because there may be individuals in populations who might erroneously think so and then end up neglecting effective treatment,” Dr. Harvima added.
Still, many people may benefit from taking vitamin D supplements. Dr. Harvima recommended following your country’s national guidelines for daily vitamin D intake.
“In countries with short daylight in winter, like in Finland,” one might consider a higher dose of vitamin D, perhaps some 20–50 micrograms a day,” Dr. Harvima said.
In the United States, the current daily recommendations for vitamin D include:
Nov 28, 2021 · Vitamin D shows anti-proliferative and pro-apoptotic effects in vitro on both melanocytes and keratinocytes. Ultraviolet (UV) exposure is the leading environmental risk factor for cutaneous malignant melanoma (CMM) and non-melanoma skin cancer (NMSC).
- Benefits of Vitamin D, Risks of D Deficiency. Vitamin D helps keep your bones strong by regulating calcium levels. Maintaining adequate amounts of the vitamin is essential for your bone health.
- Benefits of Sun Protection, Risks of Sun Exposure. In contrast, there is good evidence for the multiple benefits of sun protection. Controlled studies have shown that regular use of an SPF 15 or higher broad-spectrum sunscreen reduces your chances of developing squamous cell carcinoma by about 40 percent, melanoma by 50 percent and premature skin aging by 24 percent.
- Does Sunscreen Use Lead to Vitamin D Deficiency? High-SPF sunscreens are designed to filter out most of the sun’s UVB radiation, since UVB damage is the major cause of sunburn and can lead to skin cancers.
- Damage Before You Know It. The truth is, it doesn’t take much sun exposure for the body to produce vitamin D. Even committed proponents of unprotected sun exposure recommend no more than 10 to 15 minutes of exposure to arms, legs, abdomen and back, two to three times a week, followed by good sun protection.
Feb 25, 2015 · Vitamin D, skin cancer risk & prognosis. Exposure to the sun causes both skin cancer and vitamin D production. Cutaneous production of vitamin D is initiated by exposure to UV-B radiation. Serum concentrations of 25-hydroxyvitamin D (25 (OH)D) of 50 nmol/l or higher are classed as sufficient.
- Candy Wyatt, Candy Wyatt, Rachel E Neale, Robyn M Lucas, Robyn M Lucas
- 2015
Jan 11, 2023 · Taking a Vitamin D Supplement May Lower Skin Cancer Risk, New Study Finds. Fewer cases of skin cancer were observed in those who supplement this essential nutrient. By. Adam Meyer. Published on January 11, 2023. Reviewed by Dietitian. Jessica Ball, M.S., RD.
Dec 23, 2022 · Our literature review revealed that that vitamin D derivatives, such as 1,25 (OH)2D3 or 20 (OH)D3 can effectively reduce the proliferation of skin cancer cells by contributing in the inhibition of cell growth and development, highlighting vitamin D’s role as good prognostic factor.
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related to: is vitamin d good for your skin cancerInfo On An Rx Treatment Option For Adults With BRAF+ Unresectable Or Metastatic Melanoma. Hear People Share Their Experiences With A BRAF+ Metastatic Melanoma Rx Treatment Option.
