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   What is limited scleroderma?

   • A subtype of limited scleroderma is also known as CREST syndrome. CREST is an acronym for its most prominent clinical features: Calcinosis: calcium deposits under the skin and sometimes in tissues. Raynaud’s phenomenon: an exaggerated response to ambient temperatures making the skin of the fingers or toes cold, numb or tingling with color changes.

   Types of Scleroderma | Johns Hopkins Medicine

   www.hopkinsmedicine.org/health/conditions-and-diseases/scleroderma/types-of-scleroderma

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   Is scleroderma life threatening?

   • Most people with scleroderma don’t experience life-threatening complications. You have a higher risk of severe complications if you have systemic scleroderma that affects your internal organs. Your healthcare provider will tell you what to expect and if you have an increased risk of fatal complications. Is scleroderma a serious disease?

   Scleroderma: Symptoms, Causes & Treatment Options - Cleveland Clinic

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   Can scleroderma control your life?

   • Any chronic condition is serious, including scleroderma. That’s because you’ll probably have to manage symptoms for the rest of your life. However, that doesn’t mean scleroderma will control your life. No two people’s experiences are the same. Share your concerns or worries with your healthcare provider. A note from Cleveland Clinic

   Scleroderma: Symptoms, Causes & Treatment Options - Cleveland Clinic

   my.clevelandclinic.org/health/diseases/scleroderma

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2. my.clevelandclinic.org › health › diseasesScleroderma: Symptoms, Causes & Treatment Options

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   Sep 29, 2023 · Scleroderma is more likely to cause serious complications if it affects your ability to breathe or process nutrition. It can be fatal. Systemic sclerosis has three subtypes — diffuse, limited and sine sclerosis. Diffuse sclerosis. Diffuse means spread out widely. Diffuse sclerosis causes thickened skin over larger areas at once, including ...

3. www.hopkinsscleroderma.org › patients › aboutAbout Scleroderma : Johns Hopkins Scleroderma Center

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   Increasingly, physicians use markers in the blood called autoantibodies to help determine the course of scleroderma and overall prognosis. Not every patient will produce an autoantibody, but the three most common include centromere, topoisomerase (Scl-70), and RNA polymerase 3.

4. www.hopkinsmedicine.org › types-of-sclerodermaTypes of Scleroderma | Johns Hopkins Medicine

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   • Three Types of Localized Scleroderma: Localized, Generalized and Linear
   • Three Types of Systemic Sclerosis (Scleroderma): Limited, Diffuse and Sine

   The skin is typically the only organ impacted in localized scleroderma. However, the tissue injury may extend into the structures underlying the skin, including the subcutaneous tissue, fascia, muscle or bone. Localized scleroderma skin lesions can get better or even go away.

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   Systemic sclerosis (scleroderma) affects the skin as well as what’s underneath, such as blood vessels, muscles and joints, gastrointestinal (GI) tract, kidneys, lungs and heart. The skin thickening that accompanies systemic scleroderma can cause tightening so there is a loss of flexibility and ease of movement, especially in the fingers. Facial inv...

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5. www.uptodate.com › contents › overview-of-theOverview of the treatment and prognosis of systemic sclerosis ...

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   Aug 28, 2023 · Treatment and prognosis of interstitial lung disease in systemic sclerosis (scleroderma) Treatment of Raynaud phenomenon: Initial management Treatment of Raynaud phenomenon: Refractory or progressive ischemia

6. www.ncbi.nlm.nih.gov › books › NBK430875Systemic Sclerosis (Scleroderma) - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK430875

   Apr 5, 2024 · Typically, PAH manifests late in the course of the disease, often occurring more than 10 years after the initial diagnosis of systemic sclerosis. This condition can affect 30% to 50% of individuals with systemic sclerosis, with a higher incidence observed in cases of limited cutaneous systemic sclerosis.

   • Author: Rotimi Adigun, Amandeep Goyal, Anis Hariz

   • Published: 2022/05/08

7. www.yalemedicine.org › conditions › sclerodermaScleroderma > Fact Sheets > Yale Medicine

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   Limited cutaneous systemic sclerosis typically causes thickening of the skin on the forearms, hands, lower legs, feet, face, and neck. It begins gradually and progresses slowly.

8. www.healthline.com › health › sclerodermaSystemic Sclerosis (Scleroderma): Pictures, Symptoms, Causes

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   Feb 8, 2023 · Causes. Risk factors. Symptoms. Pictures. Diagnosis. Complications. Treatment. Outlook. FAQs. Systemic sclerosis (scleroderma) causes the body to destroy healthy tissue. It can change the...