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  5. Consider an oral treatment for adults with Major Depressive Disorder. Talk to your doctor. Learn how it's different, view trial results and access resources for savings and support.

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  2. Oct 10, 2023 · 1. Feeling sad or empty. Mood changes are one of the most common symptoms of depression. A person who has depression may feel sad or low for extended periods. They may also say that they...

  3. Oct 14, 2022 · Symptoms. Although depression may occur only once during your life, people typically have multiple episodes. During these episodes, symptoms occur most of the day, nearly every day and may include: Feelings of sadness, tearfulness, emptiness or hopelessness. Angry outbursts, irritability or frustration, even over small matters.

    • Hopeless outlook. People who are depressed often experience feelings of hopelessness, though this is not the same across all races and ethnicities. Hispanic and Latino individuals are the most likely to report feeling hopeless “all or most of the time,” followed by people of two or more races, according to a recent National Health Interview Survey.
    • Loss of interest. Depression can take the pleasure or enjoyment out of the things people love. A loss of interest in or withdrawal from activities that were previously looked forward to — sports, hobbies, going out with friends — is frequently a sign of major depression.
    • Increased fatigue and sleep problems. Part of the reason that people living with depression might stop doing things they enjoy is because they feel very tired.
    • Anxiety. Depression and anxiety often occur together. Symptoms of anxiety can include: nervousness, restlessness, or a sense of tension. feelings of danger, panic, or dread.
    • Persistent low mood. Many of us feel down from time to time, but when this feeling just won’t go away, it may mean you’re experiencing depression. You might feel like you’re continually out of sorts.
    • Loss of interest or pleasure in things you once enjoyed. “What’s the point?” and “Why bother?” are phrases you might say describe your mood for a few weeks straight.
    • Feelings of guilt, hopelessness, or worthlessness. Many people with depression can feel overwhelming guilt about past actions or events, or even feel guilty about being depressed.
    • Loss of sex drive. When you’re depressed, your desire for sex may wane. You may start to wonder what happened to your sex drive. This can lead to more guilty feelings, especially if your partner is having difficulty understanding why you no longer want this type of intimacy.
  4. If you have been experiencing some of the following signs and symptoms, most of the day, nearly every day, for at least 2 weeks, you may have depression: Persistent sad, anxious, or “empty” mood. Feelings of hopelessness or pessimism. Feelings of irritability, frustration, or restlessness.

  5. Feb 28, 2018 · Physical pain. Physical symptoms, such as body pain, headaches, cramps, and digestive problems also can occur. Younger children with depression commonly report physical pain symptoms. They may ...

  6. Jan 13, 2023 · Overview. What is depression? Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest in things and activities you once enjoyed. It can also cause difficulty with thinking, memory, eating and sleeping. It’s normal to feel sad about or grieve over difficult life situations, such as losing your job or a divorce.

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