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  1. Nov 28, 2021 · Vitamin D shows anti-proliferative and pro-apoptotic effects in vitro on both melanocytes and keratinocytes. Ultraviolet (UV) exposure is the leading environmental risk factor for cutaneous malignant melanoma (CMM) and non-melanoma skin cancer (NMSC).

  2. Dec 23, 2022 · Vitamin D has been associated with its potential effect as chemopreventive agent on skin cancer therapy. This systematic review with a total of 18 studies has revealed the tremendous potential of vitamin D in the management of skin cancer, including melanoma, squamous cell carcinoma, or basal cell carcinoma.

    • 10.2147/CMAR.S389591
    • 2022
    • Cancer Manag Res. 2022; 14: 3551-3565.
  3. There is a paucity of evidence-based recommendations for the optimal 25(OH)D levels in patients with cancer and the role of Vit D supplementation for primary or secondary prevention of cancer. Well-designed and sufficiently powered randomized clinical trials are necessary to assess the clinical appl …

    • Afsane Bahrami, Amirhossein Sahebkar
    • 2020
  4. Therapeutic supplemental vitamin D has also been reported to reduce cell growth in both melanoma and non-melanoma skin cancer. This paper aims to describe the existing research studies that discuss the potential and role of vitamin D in the management of skin cancer.

  5. Jan 11, 2023 · Vitamin D deficiency is a rapidly modifiable risk factor in critically ill patients. •. The 25 (OH)D level is a relatively stable and now readily available laboratory value after the hyperacute phase of acute illness/outside the initial phase of major surgery that reliably detects vitamin D deficiency (<20 ng/ml). •.

    • 10.3389/fmed.2022.1083760
    • 2022
    • Front Med (Lausanne). 2022; 9: 1083760.
  6. Oct 1, 2020 · Vitamin D Benefits: Effects on Bones, Depression, Cancer, and COVID-19. Reviews Health. The science-backed benefits of vitamin D and how to get enough of it. Written by Shaena...

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  8. Feb 1, 2024 · Improved treatment outcomes for non-melanoma skin cancers can be achieved if Vitamin D (Vit D) is used as a neoadjuvant prior to photodynamic therapy (PDT). However, the mechanisms for this effect are unclear. Vit D elevates protoporphyrin (PpIX) levels within tumor cells, but also exerts immune-modulatory effects.

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