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Aug 28, 2023 · Von Willebrand disease is a bleeding disorder caused by the qualitative or quantitative deficiency of the pro-von Willebrand factor. Affected people may complain of excessive bruising, prolonged bleeding from mucosal surfaces, and prolonged bleeding after minor trauma. This activity describes the evaluation and management of Von Willebrand ...
- Ayan Sabih, Hani M. Babiker
- 2023/08/28
- 2019
Apr 16, 2024 · von Willebrand disease (VWD) is a bleeding disorder. It can be inherited or, less commonly, it can develop later in life (this type of VWD is not heritable and is referred to as acquired von Willebrand syndrome [AVWS]). The amount of bleeding and need for treatment varies from person to person, with some never needing treatment (or even knowing ...
Initiation of hormonal therapy, such as oral contraceptive pills or levonorgestrel IUD. Use tranexamic acid, starting on the first day of menses and continuing for 3-5 days with each cycle. Use desmopressin, starting on the first day of menses and given daily for 1-3 days with each cycle. A or B.
Feb 1, 2024 · von Willebrand disease (VWD), the most common inherited bleeding disorder, results when patients either do not make enough von Willebrand factor (VWF) or make defective VWF. The pathophysiology of this disorder is complex but needs to be understood to interpret the diagnostic tests. Most patients have mild to moderate symptoms and can be adequately counseled and managed by a general internist ...
Nov 24, 2016 · Von Willebrand’s disease is subdivided into types 1, 2, and 3. 11 Type 1, which accounts for 70 to 80% of cases, is characterized by a quantitative deficiency of von Willebrand factor. Type 2 ...
- Frank W G Leebeek, Jeroen C J Eikenboom
- 2016
Hematology. Von Willebrand disease (VWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. [1] It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion.
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What is von Willebrand disease (vWD)?
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What is acquired von Willebrand disease?
Abstract. Most commonly inherited bleeding disorder, first described in Aland Islands by Erik von Willebrand. It occurs as a result of decrease in plasma levels or defect in von Willebrand factor which is a large multimeric glycoprotein. Monomers of this glycoprotein undergo N-glycosylation to form dimers which get arranged to give multimers.
