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   Does von Willebrand disease affect pregnancy and delivery?

   • Given the wide heterogeneity of phenotypes and of the underlying pathophysiological mechanisms associated with the disorder, pregnancy and delivery in von Willebrand disease (VWD) represent a significant clinical challenge.

   PREGNANCY AND DELIVERY IN WOMEN WITH VON WILLEBRAND DISE…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7604852/

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   Can von Willebrand disease be cured?

   • Even though von Willebrand disease has no cure, treatment can help prevent or stop bleeding episodes. Your treatment depends on: Your doctor might suggest one or more of the following treatments to increase your von Willebrand factor, strengthen blood clots or control heavy menstrual bleeding: Desmopressin.

   Von Willebrand disease - Diagnosis & treatment - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/von-willebrand-disease/diagnosis-treatment/drc-20354984

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   What is von Willebrand disease?

   • Von Willebrand disease is a lifelong bleeding disorder in which your blood doesn't clot properly. People with the disease have low levels of von Willebrand factor, a protein that helps blood clot, or the protein doesn't perform as it should. Most people with the disease are born with it, having inherited it from one or both parents.

   Von Willebrand disease - Symptoms & causes - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/von-willebrand-disease/symptoms-causes/syc-20354978

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   What are the risk factors for von Willebrand disease?

   • The main risk factor for von Willebrand disease is having a family history of it. Parents pass the gene for the disease to their children. Rarely, the disease skips generations. The disease is usually an "autosomal dominant inherited" disorder, which means you need a mutated gene from only one parent to get the disease.

   Von Willebrand disease - Symptoms & causes - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/von-willebrand-disease/symptoms-causes/syc-20354978

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2. www.mayoclinic.org › diseases-conditions › vonVon Willebrand disease - Diagnosis & treatment - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › von

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   Oct 26, 2021 · Even though von Willebrand disease has no cure, treatment can help prevent or stop bleeding episodes. Your treatment depends on: The type and severity of your condition

3. www.ncbi.nlm.nih.gov › pmc › articlesPREGNANCY AND DELIVERY IN WOMEN WITH VON WILLEBRAND DISEASE

   www.ncbi.nlm.nih.gov › pmc › articles

   General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.

   • Author: Giancarlo Castaman, Paula D. James
   • DOI: 10.1111/ejh.13250

   • Publish Year: 2019
   • Published: 2019/08

4. www.mayoclinicproceedings.org › article › S0025-6196Treatment of von Willebrand's Disease - Mayo Clinic Proceedings

   www.mayoclinicproceedings.org › article › S0025-6196

   Download Full Issue. Treatment of von Willebrand's Disease. LOUIS M. ALEDORT, M.D. DOI: https://doi.org/10.1016/S0025-6196 (12)61203-8. Treatment of von Willebrand's Disease. Early recognition that plasma infusions could correct the prolonged bleeding time and factor VIII deficiency in von Willebrand's disease (vWD) prompted major research efforts.

   • Author: Louis M. Aledort

   • Publish Year: 1991

5. www.mayo.edu › research › clinical-trialsA Study of Reproductive Health Decision-Making ... - Mayo Clinic

   www.mayo.edu › research › clinical-trials

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   The purpose of this study is to assess the decision-making process in women who have Von Willebrand disease, regarding their attitudes and beliefs about contraception, pregnancy, and assisted reproduction and how these attitudes and beliefs affect choices and the management of bleeding risk during pregnancy. Participation eligibility.

6. www.mayoclinicproceedings.org › article › S0025-6196Von Willebrand Factor: Clinical Features of Inherited and ...

   www.mayoclinicproceedings.org › article › S0025-6196

   Levels of vWF are also high during pregnancy and in fetal and cord blood; fetal and neonatal plasma contains high-molecular-weight multimers similar to those in Weibel-Palade bodies of endothelial cells and α-granules of platelets and to those found in patients with thrombotic thrombocytopenic purpura. 3.

7. www.cdc.gov › von-willebrand › femaleVon Willebrand Disease and Pregnancy

   www.cdc.gov › von-willebrand › female

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   May 15, 2024 · Key points. With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. Close monitoring throughout pregnancy is important for women with VWD. Women with VWD are at risk for serious bleeding after delivery. Pregnancy and childbirth.