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    • Charleston. Population: 156,255. Population Density: 1,413 per square mile. Total Area: 110.55 square miles. Year Established: 1783 as city. Source: Pixabay. The city of Charleston is the seat of government for Charleston County and the largest city in South Carolina, with a population of 156,255.
    • Columbia. Population: 138,104. Population Density: 1,015 per square mile. Total Area: 136 square miles. Year Established: 1805, 1854 as city. Source: Wikimedia. The city of Columbia serves as the seat of government for the state of South Carolina in the United States.
    • North Charleston. Population: 118,328. Population Density: 1,527 per square mile. Total Area: 77.50 square miles. Year Established: 1972. Source: Wikimedia. The city of North Charleston is South Carolina’s third-largest, behind Charleston and Columbia.
    • Mount Pleasant. Population: 95,393. Population Density: 1,933 per square mile. Total Area: 49.34 square miles. Year Established: 1680 as settlement. Source: Wikimedia.
    • Charlotte. Incorporated: 1768. Population: 874,579. 10-year growth: 20 percent. Land area: 297 square miles. Region: Piedmont. County: Mecklenburg. Named for: Princess Charlotte Sophia of Mecklenburg-Strelitz, George III’s queen.
    • Raleigh. Incorporated: 1792. Population: 467,665. 10-year growth: 16 percent. Land area: 142 square miles. Region: Research Triangle. Counties: Wake (seat), Durham.
    • Greensboro. Incorporated: 1808. Population: 299,035. 10-year growth: 11 percent. Land area: 126 square miles. Region: Piedmont Triad. County: Guilford. Named for: Gen.
    • Durham. Incorporated: 1869. Population: 283,506. 10-year growth: 24 percent. Land area: 107 square miles. Region: Research Triangle. Counties: Durham (seat), Wake, Orange.
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    • Hash-Mark1. Charlotte
    • Hash-Mark2. Raleigh
    • Hash-Mark3. Greensboro
    • Hash-Mark4. Durham
    • Hash-Mark5. Winston-Salem
    • Hash-Mark6. Fayetteville
    • Hash-Mark7. Cary
    • Hash-Mark8. Wilmington
    • Hash-Mark9. High Point

    Charlotte is the largest city in North Carolina, with a population of 888,655. Charlotte is located in Mecklenburg County and is also the state’s main financial and cultural hub. Due to its fantastic weather, a wide variety of job opportunities, and affordable living, the Charlotte metropolitan area has been attracting many new residents in recent ...

    With 474,240 residents, Raleigh is the second-biggest city in North Carolina by population. It's also the state's capital. Known as “the City of Oaks,” Raleigh is famous for its gorgeous Oak trees that line the city streets. It is also the largest city in the Research Triangle region of Piedmont County, an area home to three major research universi...

    Greensboro is also one of the biggest cities in North Carolina and the largest in the Piedmont Triad metropolitan region – which also includes nearby cities of Winston-Salem and High Point. The city has many notable attractions, including the Greensboro Science Center, the Weatherspoon Art Museum, and the International Civil Rights Museum. The econ...

    Durham is another one of the major cities in North Carolina. It is the second largest city in the Research Triangle and the fourth largest in the state overall. It’s known for being the home of Duke University and North Carolina Central University, making it a major powerhouse in the Research Triangle Region. The universities are also significant c...

    Winston-Salem is another one of the biggest cities in North Carolina by population as well as being the second-largest in the Piedmont Triad. It’s a laidback college town home to several prominent universities, including Wake Forest University, Winston-Salem University, and UNC School of Arts. Winston-Salem offers all the benefits of living in a sm...

    Fayetteville is a city in Cumberland County in the southcentral region of the state. It’s notable for being the home of Fort Bragg, one of the largest army bases in the United States, with over 50,000 military personnel. The Department of Defense is the city’s largest employer, followed by the Cape Fear Valley Health System and Cumberland County Pu...

    Cary is a large city in Wake and Chatham counties, considered part of the Raleigh metropolitan area. It offers a small-town ambiance with plenty of amenities and job opportunities. Several technology companies have a presence in Cary, including ABB, Epic Games, and Lockheed Martin 3D Solutions. It also features a very low crime rate, and is one of ...

    Wilmington is a port city on the Atlantic Ocean, situated along the state’s southern coast. The city is known for its sandy beaches, mild weather, and bustling boardwalk. It’s also home to EUE/Screen Gems Studios, the largest film and television studio outside of Hollywood, which has produced major films like Iron Man 3, The Conjuring, and Sleepy H...

    High Point is a city in the Piedmont Triad and the 9th largest in the state by population. Known as the “Home Furnishings Capital of the World,” High Point is a major global producer of furniture and hosts a bi-annual trade show that is visited by furniture makers from around the globe. Beyond furniture, it also offers a diverse economy supported b...

    • Charlotte, NC. The bustling business and entertainment hub of North Carolina, Charlotte is the state’s most populous city. According to the 2020 census, the “Queen City” had around 874,579 residents, nearly double the population of any other NC city.
    • Raleigh, NC. North Carolina’s capital city is Raleigh, home to 467,665 residents as of the 2020 census and a common tourist destination. It’s one of the state’s most populated areas, and an integral part of the “Research Triangle”, which recognizes the importance of Raleigh, Durham, and Chapel Hill in the research field.
    • Greensboro, NC. Located in northern North Carolina, Greensboro has around 299,035 residents (2020 census). Its central location makes it an easily accessible destination for North Carolinians, especially those in the Raleigh-Durham area, as well as many Virginians.
    • Durham, NC. Durham, the “Bull City”, is a quick 30-minute drive from Raleigh and another integral part of the Research Triangle. As of the 2020 census, it had a population of 283,506 people.
  2. Nov 6, 2023 · Using the latest Census data, we detail the 100 biggest cities in South Carolina. You can all see a comprehensive list of all 238 cities and places in South Carolina.

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  3. Florence. Charleston (Population: 150,227) Charleston is the largest city in South Carolina by population, with 150,227 residents. It’s also the principal city in the Charleston MSA, which covers Charleston, Berkley, and Dorchester Counties.

  4. Mar 30, 2023 · Here are the ten biggest cities in South Carolina, in order of the highest to lowest populations: Charleston, SC Downtown Charleston, SC. Photo by: James Willamor. Anyone who appreciates delightful, colorful architecture and white sand beaches will love Charleston, known as the “Holy City”. With just over 150,000 residents as of the 2020 ...

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