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  1. Sep 11, 2023 · One of the main differences is that hemophilia primarily affects males, whereas VWD affects both females and males. Another difference is that VWD tends to be milder than hemophilia. If...

  2. Feb 14, 2014 · Although similar, hemophilia and vWD have important differences. Bleeding location and severity vary more for vWD patients than for hemophilia patients. vWF targets skin and mucous membranes (the lining of the nose, mouth, intestines, uterus, and vagina), so a deficiency causes more bleeding at these sites.

  3. Oct 26, 2021 · Many people with von Willebrand disease also have low levels of factor VIII, another protein that helps in clotting. Factor VIII is involved in another inherited clotting disorder called hemophilia. But unlike hemophilia, which mainly affects males, von Willebrand disease affects males and females and is usually milder.

  4. Jun 22, 2022 · The numbers vary because people may have bleeding issues, but aren’t diagnosed with von Willebrand disease. In some cases, people have had bleeding issues for many years before they have a firm diagnosis. Advertisement Is von Willebrand disease the same as hemophilia? von Willebrand is similar to hemophilia but typically causes less severe ...

  5. Apr 29, 2021 · This is in contrast to hemophilia A, for which a continuous innovative path has led to novel treatment modalities. Despite current VWD management being considered effective, quality-of-life studies consistently reveal a higher than anticipated burden of VWD on patients, which is particularly true for women.

    • Cécile V Denis, Sophie Susen, Peter J Lenting
    • 2021
  6. In type 2 N, there is impaired binding of VWF to factor VIII and significant reduction in factor VIII levels (ie, to 1 to 5%) similar to that seen in hemophilia A.

  7. Jan 12, 2021 · These evidence-based guidelines from the American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), the National Hemophilia Foundation (NHF), and the World Federation of Hemophilia (WFH) are intended to support patients, clinicians, and health care professionals in their decisions about management of VWD.