Search results
Apr 13, 2021 · The World Health Organization assigns international nonproprietary names (INN), also known as common names, to compounds upon request from drug developers. Structures of INNs are publicly available and represent a source, albeit underused, to understand trends in drug research and development.
- Marta Serafini, Sarah Cargnin, Alberto Massarotti, Gian Cesare Tron, Tracey Pirali, Armando A Genazz...
- 2021
The International Nonproprietary Names (INN) Programme is a core activity embedded in the normative functions of WHO and has served the global public health and medicines community for over sixty years.
People also ask
Why do some drugs have more than one non-proprietary name?
What is the INN-USAN-harmonized nomenclature scheme for substances for cell therapy?
What is a nonproprietary name?
Which substances are given a one-word name?
- Natural Sources
- 3.1: Drugs Obtained from Various Parts of The Plant
- Semi-Synthetic Sources
- Synthetic Sources
3.1.1 Plants as Drug Sources
Among the natural sources, plants contribute to a vast majority of drugs. Extracts from plants may either be used without further processing (crude drugs) or with technical processing (prepared drugs). Although the earliest plant source for drugs was the leaf, other parts of plants were also later exploited for drug extraction. A few drugs can be extracted from more than one plant part (Box 3.1).
The pharmacologically active principles derived from plants may be of different categories, as mentioned below: 1. Alkaloids 1.1. Alkaloids (meaning “alkali-like”) are complex, organic, bitter-tasting, alkaline- and nitrogen-containing compounds, mostly obtained from plants. They may also be obtained from animal sources. 1.2. These are readily solu...
When the nucleus of the drugs obtained from natural sources is kept intact while altering the chemical structure, the resultant products are semi-synthetic drugs.Homatropine (from atropine), heroin (from morphine), bromoscopolamine (from scopolamine) and ampicillin (from penicillin) are some of the examples. As evident from these examples, semi-synthetic dr...Unlike semi-synthetic drugs, synthetic drugs are those in which both the nucleus and the chemical structure are altered or modified.These are exclusively prepared in the laboratory. One of the earliest synthetic drugs was sulphonamide, which began with the synthesis of prontosil dye. A vast majority of the modern-day drugs are...- Avinash Arivazhahan
- 2019
Oct 11, 2023 · Drugs are also known by generic, non- proprietary or official names. This is the name given to a drug after it might have been found to be of therapeutic use. It is the name with which the drug is described in official books of reference like pharmacopoeias.
More than 50 years ago, WHO established the International Nonproprietary Name (INN) Expert Group/WHO Expert Committee on Specifications for Pharmaceutical Preparations, to assign nonproprietary names to medicinal substances, so that each substance would be recognized globally by a unique name.
Dec 15, 2023 · International Non-proprietary Names (INNs) are the standardized, generic names assigned to drugs by the World Health Organization (WHO). These unique, non-branded names aim to: Prevent confusion: INNs avoid the potential for confusion caused by brand names, which can vary depending on the country and manufacturer.
Since the time when insulin human became the first recommended INN (rINN) for a recombinant substances, the range of biological/biotechnological substances has increased in size and complexity. For example, new stems have been introduced for tissue plasminogen activators (-plase) among other groups.
