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  1. Mar 24, 2023 · TV and film icons like Geena Davis, Rita Moreno, and Faye Dunaway have guest-starred on "Grey's Anatomy" over 19 seasons.

    • Henry Blodget
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  3. Skyler Shaye was born on 14 October 1986 in Los Angeles, California, USA. She is an actress and producer, known for Grey's Anatomy (2005), Bratz (2007) and Superbabies: Baby Geniuses 2 (2004). She has been married to Christian Lopez since 10 October 2022.

    • Rosanna Arquette. Episode: Season 2, episode 11: "Owner of a Lonely Heart" Arquette made an early-series appearance in the second season, playing Constance Ferguson, a prisoner who swallowed razor blades in order to be admitted to Seattle Grace.
    • Kyle Chandler. Episodes: Season 2, episode 16: "It's the End of the World"; season 3, episode 17: "Some Kind of Miracle" Before he was Coach Taylor, Chandler appeared in two episodes of Grey's as Dylan Young.
    • Christina Ricci. Episode: Season 2, episodes 16 and 17: "It's the End of the World" and "As We Know It" Ricci turned to the small-screen in an episode that had her portraying Hannah, a paramedic who, by trying to stop the bleeding of an injured patient, put her hand on the wound.
    • Tessa Thompson. Episode: Season 2, episode 26: "Deterioration of the Fight or Flight Response" Before Black Panther and Thor: Ragnarok, Thompson made a brief appearance as Camille Travis, Richard Webber's niece, in the series' second season.
    • Madeline Boardman
    • Leslie Odom Jr. Years before he would pick up a Tony for his role of Aaron Burr in the runaway Broadway hit Hamilton, Leslie Odom Jr. popped up in one 2008 episode of Grey's Anatomy.
    • Sarah Paulson. A few years before she earned her first Golden Globe and Emmy, Sarah Paulson booked a one-episode gig on Grey's Anatomy. The actress played Dr. Ellis Grey in a 2010 flashback episode, depicting Meredith's mother during her residency.
    • Demi Lovato. Back in their Sonny with a Chance days, Demi Lovato stopped by one 2010 episode of Grey's Anatomy. The pop star played Hayley May, a patient whose condition was difficult to diagnose and made those around her doubt her symptoms.
    • Danny Strong. After saying goodbye to Gilmore Girls' Doyle McMaster, Danny Strong played a man named Paul in one 2012 episode of Grey's Anatomy. He visits the hospital after getting attacked by a lion belonging to his girlfriend.
    • Lia Fairchild
    • Abigail Breslin. Oscar nominee Abigail Breslin was just 9 years old when "Grey's Anatomy" premiered in 2005, but she already had an impressive start on her acting resume, having begun at the age of 3 in a Toys "R" Us commercial and followed that up with 2002's "Signs" opposite Mel Gibson and Joaquin Phoenix.
    • Demi Lovato. Singer, songwriter, and actor Demi Lovato got her start as one of the kids on "Barney & Friends." She would go on to be a fixture of the Disney Channel, appearing in movies like "Camp Rock" and "Princess Protection Program," as well as playing the titular role in the series "Sonny with a Chance."
    • Alyssa Milano and Holly Marie Combs. In 2019, ABC had a "Cast From the Past" week which placed characters from shows gone by on current ABC shows. Per the ABC website, some of those shows being honored were "Cheers," "Girlfriends," and "Charmed."
    • Rachel Brosnahan. Less than five years into her acting career, "The Marvelous Mrs. Maisel" star Rachel Brosnahan snagged a coveted spot on "Grey's Anatomy" in a Season 9 episode.
  4. Caterina Scorsone is a Canadian-American actress. She is best known for playing Dr. Amelia Shepherd on the ABC medical drama Grey's Anatomy (2010–present) and its spin-offs Private Practice (2010–2013) and Station 19 (2020–2024).

  5. Feb 20, 2024 · While fans wait to see if her dream comes to fruition, look back on 27 of the biggest stars who have already made Grey's cameos. 1. Demi Lovato. A then-18-year-old Lovato guested in Season 6 as...

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