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Escherichia virus Lambda. Bacteriophage Lambda Structural Model at Atomic Resolution [1] Enterobacteria phage λ (lambda phage, coliphage λ, officially Escherichia virus Lambda) is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli (E. coli). It was discovered by Esther Lederberg in 1950. [2]
Abstract. Molecular genetic research on bacteriophage lambda carried out during its golden age from the mid 1950's to mid 1980's was critically important in the attainment of our current understanding of the sophisticated and complex mechanisms by which the expression of genes is controlled, of DNA virus assembly and of the molecular nature of ...
- Sherwood R. Casjens, Roger W. Hendrix
- 10.1016/j.virol.2015.02.010
- 2015
- 2015/05
The developmental pathways of many double-stranded DNA (dsDNA) viruses, both prokaryotic and eukaryotic, are remarkably similar. In viruses as diverse as bacteriophage λ, and the herpesviruses, DNA replication proceeds through a rolling circle mechanism where the circular genome serves as a template for the synthesis of linear concatemers multiple genomes in length. Concurrently, viral gene ...
- Michael Feiss, Carlos Enrique Catalano
- 2013
- 2005
May 17, 2024 · Bacteriophage lambda, a member of the Siphoviruses with a long and flexible tail, has served as a crucial model for bacteriophage biology and genetics since its discovery in the 1950s 1,2,3. The ...
Apr 7, 2010 · Bacteriophage λ is a temperate phage, which, upon infection of Escherichia coli, enters either the lytic or lysogenic replication pathway. The latter is defined by the integration of the λ prophage within the bacterial host genome, where it is quiescently inherited by daughter cells.
- Paul C. M. Fogg, Heather E. Allison, Jon R. Saunders, Alan J. McCarthy
- 10.1128/JVI.02177-09
- 2010
- J Virol. 2010 Jul; 84(13): 6876-6879.
Bacteriophage lambda has a double-stranded DNA genome and a long, flexible, non-contractile tail encoded by a contiguous block of 11 genes downstream of the head genes. The tail allows host recognition and delivery of viral DNA from the head shell to the cytoplasm of the infected cell. Here, we present a high-resolution structure of the tail ...
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Feb 3, 2020 · The Bacteriophage Lambda (Cold Spring Harbor Laboratory Press 1971). Roux, S. et al. Ecology and evolution of viruses infecting uncultivated SUP05 bacteria as revealed by single-cell- and meta ...
