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  1. Jul 17, 2023 · Borrelia burgdorferi is a pathogenic spirochete responsible for Lyme disease via a tick vector. This spirochete causes a characteristic annular rash, arthritis, carditis, and in late stages, encephalopathy. This activity reviews the cause of lyme disease, its presentation and diagnosis and highlights the role of the interprofessional team in ...

    • Randi Tatum, Anthony L. Pearson-Shaver
    • 2023/07/17
    • PBCGME, Nova Southeastern University
  2. Nov 11, 2014 · The spirochaete bacterium Borrelia burgdorferi sensu lato is the causative agent of Lyme disease, the most common tick-borne infection in the northern hemisphere. There is a long-standing debate regarding the role of pleomorphic forms in Lyme disease pathogenesis, while very little is known about the characteristics of these morphological variants.

    • Leena Meriläinen, Anni Herranen, Armin Schwarzbach, Leona Gilbert
    • 10.1099/mic.0.000027
    • 2015
    • 2015/03
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  4. Borrelia burgdorferi is a microaerophile, requiring small amounts of oxygen in order to undergo glycolysis and survive. Like all other Borrelia sps., this bacterium is also gram-negative and a spirochete. Borrelia colonies are often smaller, rounded, and white with an elevated center. [7] B. burgdorferi possesses flagella that allow it motility.

  5. Jun 27, 2022 · Borrelia burgdorferi was initially defined as a new species of the genus Borrelia in 1984 based on the characterization of other species of the same genus. In recent years, the classification of B. burgdorferi has been modified based on its phenotypic and genotypic characteristics.

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  6. Feb 21, 2017 · Borrelia burgdorferi motility and associated regulation. Motility of B. burgdorferi is driven by multiple flagellum in the periplasmic space that are comprised of an inner membrane anchored basal body, hook, and filament. Coordinated rotation of the flagellar motors drive the direction of swimming or causes flexing of the spirochete.

    • Jenny A. Hyde
    • 10.3389/fimmu.2017.00114
    • 2017
    • Front Immunol. 2017; 8: 114.
  7. Jul 4, 2011 · Borrelia burgdorferi bacterium, CDC. Borrelia burgdorferi is a Gram-negative spirochete bacteria that is well known as the causative agent of Lyme disease. In 1982, a few years after Lyme disease was first diagnosed, it was determined that B. burgdorferi was being transmitted to humans by ticks. Since then, it's genome has been fully sequenced ...

  8. Jan 1, 2016 · Microbiology. Borrelia burgdorferi is a spiral-shaped, microaerophilic two-membrane bacterium that is primarily extracellular. B. burgdorferi is one of the few pathogenic bacteria that can survive without iron, instead requiring manganese for proper function of some of its enzymes. The bacterium is covered with flagella and peptidoglycan and ...

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