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Oct 9, 2023 · Borrelia-specific versus common virulence factors. Virulence factors can be classified as pathogen-specific (no orthologous protein in other bacteria) and common (one or more orthologous proteins in different pathogenic bacteria) based on whether the virulence determinant is present in a single species or it is found in multiple different ...
- Biology of Infection with Borrelia burgdorferi - PMC
The spirochete Borrelia burgdorferi is a tick-borne obligate...
- Pathogenicity and virulence of Borrelia burgdorferi - PubMed
Virulence Factors. Infection with Borrelia burgdorferi often...
- Biology of Infection with Borrelia burgdorferi - PMC
Oct 9, 2023 · The bacterial pathogen Borrelia burgdorferi, also known. as Borreliella burgdorferi, is the causative agent of Lyme. disease (LD) and is transmitted to humans through. Ixodes ticks. LD is the most ...
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Jul 17, 2023 · Borrelia burgdorferi is a pathogenic spirochete responsible for Lyme disease via a tick vector. This spirochete causes a characteristic annular rash, arthritis, carditis, and in late stages, encephalopathy. This activity reviews the cause of lyme disease, its presentation and diagnosis and highlights the role of the interprofessional team in ...
- Randi Tatum, Anthony L. Pearson-Shaver
- 2023/07/17
- PBCGME, Nova Southeastern University
Feb 11, 2016 · This virulence factor significantly reduces the effectiveness of the adaptive immune system in responding to the invader. B. burgdorferi also use the tactic of binding to complement H factor through BbCRASPs . These H factors are used by the host immune system to avoid activating complement for self cells.
B. burgdorferi is a microaerobic, motile spirochete with seven to 11 bundled perisplasmic flagella set at each end that allow the bacterium to move in low- and high-viscosity media alike, which is related to its high virulence factor. Metabolism. B. burgdorferi is a slow-growing microaerophilic spirochete with a doubling time of 24 to 48 hours.