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  1. To investigate the effects of fever therapy compared with no fever therapy in a wide population of febrile adults. Design Systematic review with meta-analyses and trial sequential analyses of randomised clinical trials. Data s Ources CENTRAL, BIOSIS, CINAHL, MEDLINE, Embase, LILACS, Scopus, and Web of Science Core Collection, searched

  2. Nov 23, 2022 · Fever, an elevation in core body temperature above the daily range for an individual, is a characteristic feature of most infections but is also found in a number of noninfectious diseases such as autoimmune and autoinflammatory diseases. Definitions of normal body temperature, the pathophysiology of fever, the role of cytokines, and the ...

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  4. Jul 12, 2022 · Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses. BMJ 2022 ; 378 doi: https://doi.org/10.1136/bmj-2021-069620 (Published 12 July 2022) Cite this as: BMJ 2022;378:e069620. Article.

    • Current Concepts
    • PREDOMINANT CAUSES OF FEVER
    • Pneu. carinii
    • Streptococcus pneumoniae
    • Clostridium difficile, cryp-
    • HIV INFECTION OR AIDS
    • INTERVENTIONS

    HILIP A. P , M.D. IZZO HE past two decades have witnessed an in-crease in the number of patients who are im-munocompromised as a consequence of a primary or secondary immunodeficiency disorder or from the use of agents that depress one or more components of the immune system. Broadly de-fined, an immunocompromised host has an alter-ation in phagocy...

    Fever of unknown cause Gram-positive or gram-negative bacteria, respiratory viruses or herpesviruses, Pneumocystis carinii (rarely) Fever of unknown cause Bacteria: gram-positive or gram-negative aerobes, anaerobes at sites of mixed infection Viruses: respiratory syncytial virus, parainfluenza virus, adenoviruses, herpes simplex virus, cytomegalovi...

    Bacteria: primarily encapsulated organisms, especially Streptococcus pneumoni-ae, Neisseria meningitidis, Haemophilus influenzae, Capnocytophaga cani-morsus (DF2) Parasites: babesia, malaria Bacteria: more common in children, although incidence of Strep. pneumoniae is increased in adults as well; other encapsulated bacteria, salmonella, enteric bac...

    Not specificNot specificCommon tract Gastrointestinal gal) with prolonged gal) neutropenia Bacterial or fungal pneu- Local or diffuse pneumo- monia with neutropenia nia (especially fungal) Cytomegalovirus about 30 with prolonged neutro- to 60 days after alloge- penia neic transplantation Mucositis or esophagitis Mucositis or esophagitis Common Not...

    tosporidia, microsporidia LiverHepatosplenic candidiasis Hepatosplenic candidiasis UncommonHepatitis, UncommonUncommonUncommonHepatitisHepatitis A, B, and C virus- (on recovery from neu- (on recovery from neu- tropenia) tropenia) Nervous systemUncommonUncommon (toxoplasma, Uncommon cholangi- tis, abscess Uncommon nocardia, cryptococcus) (listeria) ...

    LOW RISK HIGH RISK BONE MARROW KIDNEY LIVER LUNG HEART CHILDREN ADULTS History and physical exam-ination Hematologic CBC and differential count Platelets Coagulation studies Microbiologic Nose and throat Urine Stool Blood Cytomegalovirus antigen Epstein–Barr virus PCR Cerebrospinal fluid Radiologic Chest Sinus Special studies§ + (repeat daily if fe...

    Cancer Low risk High risk Begin broad-spectrum antibiotic therapy with a single parenteral agent (e.g., ceftazidime, cefepime, imipenem, meropenem) or possibly oral therapy (ciprofloxacin and amoxicillin plus clavulanate potassium). Begin broad-spectrum parenteral antibiotics with a single agent (see low risk, above) or a combination regimen. Addit...

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  5. Clinical Practice Guideline for the Evaluation of Fever and Infection in Older Adult Residents of Long-Term Care Facilities: 2008 Update by the Infectious Diseases Society of America KevinP. High, MD, MS,a Suzanne F. Bradley,MD,bcd StefanGravenstein, MD,efgh DavidR. Mehr,MD,i Vincent J. Quagliarello, MD,j Chesley Richards, MD,kl and Thomas T ...

  6. Nov 17, 2023 · TO THE EDITOR —The Society of Critical Care Medicine (SCCM) and the Infectious Diseases Society of America (IDSA) have updated their guideline for the evaluation of new-onset fever in adult intensive care unit (ICU) patients without severe immunocompromise . The update now incorporates the GRADE (Grading of Recommendations Assessment ...

  7. Jan 15, 2009 · Clinical Practice Guideline for the Evaluation of Fever and Infection in Older Adult Residents of Long-Term Care Facilities: 2008 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | Oxford Academic. Journal Article Guidelines.

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