Yahoo Web Search

Search results

1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

2. Videos

   • 

     13:10

     youtube.com

     Dengue Fever | Pathophysiology, Symptoms, Diagnosis & Treatment

     Feb 15, 2020

     968.1K Views

   • 

     5:03

     youtube.com

     Dengue Explained in 5 Minutes

     Oct 29, 2021

     341.2K Views

   • 

     5:04

     youtube.com

     What is Dengue? Causes, Signs and Symptoms, Diagnosis and treatment.

     Jul 4, 2018

     496.2K Views

   View all

3. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

   • Cached

   Apr 22, 2024 · Dengue virus infection is known to induce endoplasmic reticulum (ER) stress, triggering signaling pathways associated with ER stress during viral infections. These pathways activate genes that support cell survival and anti-viral defenses.

4. pubmed.ncbi.nlm.nih.gov › 28401256Immune-mediated cytokine storm and its role in severe dengue

   pubmed.ncbi.nlm.nih.gov › 28401256

   Both the innate and the adaptive immune systems are activated in severe dengue and contribute to the cytokine production. We discuss the immunological events elicited during a DENV infection and identify candidate cytokines that may play a key role in the severe manifestations of dengue and possible interventions.

   • Author: Anon Srikiatkhachorn, Anuja Mathew, Alan L. Rothman

   • Publish Year: 2017

5. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

   www.sciencedirect.com › science › article

   May 1, 2024 · Bleeding following dengue virus infection occurs due to multiple mechanisms including platelet activation by NS1, serotonin, and PAF, accompanied by a wide range of other coagulation abnormalities.

6. www.nature.com › articles › s41577/019/0123-xAdaptive immune responses to primary and secondary dengue ...

   www.nature.com › articles › s41577/019/0123-x

   Jan 24, 2019 · The existence of four different serotypes of dengue virus poses a challenge to vaccine development, as pre-existing immunity can lead to severe disease during infection with a heterologous...

   • Author: Ashley L St John, Ashley L St John, Abhay P S Rathore

   • Publish Year: 2019

7. People also ask

   Is dengue virus a sin or a cytokine storm?

   • Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms. Nat Rev Immunol. 2011;11 (8):532–43.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

   See all results for this question

   How does a dengue virus interact with the host cellular machinery?

   • During dengue infection, the virus interacts with the host cellular machinery responsible for 5’ capping. DENV employs multiple strategies to hijack and manipulate this process. For instance, the virus sequesters essential host factors involved in capping, such as the cap-binding complex and associated enzymes.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

   See all results for this question

   What causes severe manifestations of dengue virus disease?

   • The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

   See all results for this question

8. www.ncbi.nlm.nih.gov › pmc › articlesImmune Mediated Cytokine Storm and Its Role in Severe Dengue

   www.ncbi.nlm.nih.gov › pmc › articles

   Dengue hemorrhagic fever-associated immunomediators induced via maturation of dengue virus nonstructural 4B protein in monocytes modulate endothelial cell adhesion molecules and human microvascular endothelial cells permeability.

9. link.springer.com › article › 10Immune-mediated cytokine storm and its role in severe dengue

   link.springer.com › article › 10

   • Cached

   Apr 11, 2017 · Infection with one of the serologically related dengue viruses (DENVs) can lead to a wide range of clinical manifestations and severity. Severe dengue is characterized by plasma leakage and abnormal bleeding that can lead to shock and death.