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  1. Nov 24, 2020 · The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

  2. Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.
  3. Aug 16, 2018 · Despite the resurgence of dengue incidence in Puerto Rico, Hurricane Georges had minimal affect on the overall trajectory of dengue disease . Additionally, no confirmed cases of dengue infections were determined in emergency relief workers working in Puerto Rico following Hurricane Georges [ 27 ].

    • Mihir A. Shukla, Laila Woc-Colburn
    • 2018
  4. Jan 15, 2023 · FcR-dependent ADE is the most common mechanism for a wide range of virus infection such as HIV, influenza A, dengue and Ebola. Cells which have FcR such as monocytes, B cells, neutrophils and macrophages are easily attached by the virus-antibody complexes because the Fc region of the antibody will bind on the cell surface with FcR which leads ...

  5. This review summarizes the current knowledge on DENV epidemiology, biology, and disease aetiology in the context of prevention and protection from dengue virus disease. Keywords: ADE; DENV; DHF; antibody-dependent enhancement; dengue hemorrhagic fever; dengue virus; infection secondaire; secondary infection; virus de la dengue.

    • Sudipta Kumar Roy, Soumen Bhattacharjee
    • 2021
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  7. gue virus (DENV) in Africa is lacking. By using next-gen-eration sequencing of samples from the 2017 DENV out-break in Burkina Faso, we isolated 29 DENV genomes (5 serotype 1, 16 serotype 2 [DENV-2], and 8 serotype 3). Phylogenetic analysis demonstrated the endemic na-ture of DENV-2 in Burkina Faso. We noted discordant

  8. Apr 24, 2018 · Dengue virus (DENV), an arbovirus transmitted by mosquitoes, has become a major threat to American human life, reaching approximately 23 million cases from 1980 to 2017. Brazil is among the countries most affected by this terrible viral disease, with 13.6 million cases. DENV has four different serotypes, DENV1-4, which show a broad clinical ...

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