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  1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

    Nov 24, 2020 · There are four serotypes of dengue virus which are antigenically distinct namely DENV-1, DENV-2, DENV-3, and DENV-4 . A fifth serotype (DENV-5) has been detected using isolation and genetic sequence analysis in Sarawak state of Malaysia in October 2013 . The incubation period of dengue virus infection is 4–7 days.

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  3. pubmed.ncbi.nlm.nih.gov › 34171205Dengue virus: epidemiology, biology, and disease aetiology

    Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions. A positive-stranded enveloped RNA virus (DENV) is principally transmitted by Aedes ...

    • Sudipta Kumar Roy, Soumen Bhattacharjee
    • 2021

  4. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

    Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.

  5. onlinelibrary.wiley.com › doi › fullThe decline of dengue in the Americas in 2017: discussion of ...

    Jan 9, 2019 · However, in 2017, there was a noticeable reduction in reported dengue incidence cases within the Americas, including severe and fatal cases. Understanding the mechanism underlying dengue's incidence and decline in the Americas is vital for public health planning. We aimed to provide plausible explanations for the decline in 2017.

    • Freddy Perez, Anthony Llau, Gamaliel Gutierrez, Haroldo Bezerra, Giovanini Coelho, Steven Ault, Sula...
    • 2019

  6. www.nature.com › articles › s41467/023/44330-8Protection against symptomatic dengue infection by ... - Nature

    Jan 9, 2024 · The four dengue virus serotypes (DENV1-4) are mosquito-borne flaviviruses endemic to tropical and subtropical regions that cause the most prevalent arthropod-borne viral disease in humans.

    • Sandra Bos

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  8. www.nature.com › articles › d41586/023/02423-wDengue is breaking records in the Americas — what’s behind ...

    Jul 27, 2023 · Dengue is caused by four closely related viruses, or serotypes, which makes identifying the exact cause of the surge challenging. “There is an interaction between these serotypes, with the ...

  9. www.ncbi.nlm.nih.gov › pmc › articlesDengue virus: A global human threat: Review of literature

    Dengue is an acute viral illness caused by RNA virus of the family Flaviviridae and spread by Aedes mosquitoes. Presenting features may range from asymptomatic fever to dreaded complications such as hemorrhagic fever and shock. A cute-onset high fever, muscle and joint pain, myalgia, cutaneous rash, hemorrhagic episodes, and circulatory shock ...