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  1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

    Nov 24, 2020 · There are four serotypes of dengue virus which are antigenically distinct namely DENV-1, DENV-2, DENV-3, and DENV-4 . A fifth serotype (DENV-5) has been detected using isolation and genetic sequence analysis in Sarawak state of Malaysia in October 2013 . The incubation period of dengue virus infection is 4–7 days.

  2. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

    Dec 15, 2021 · About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus infection is especially transmitted through bites of Aedes mosquitos, hugely spread in tropical and subtropical environments, mostly found in urban and semiurban areas. Unfortunately, there is no ...

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.

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  4. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

    Apr 22, 2024 · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...

  5. www.nature.com › articles › s41467/024/47774-8Travel surveillance uncovers dengue virus dynamics and ...

    Apr 25, 2024 · We estimate that they were introduced into Cuba by at least 2016 (95% HPD 2015-12-20 to 2016-12-15, likely from Puerto Rico, posterior support = 0.77) and late 2017 (95% HPD 2017-02-20 to 2018-06 ...

  6. www.nejm.org › doi › fullDengue | New England Journal of Medicine

    Apr 12, 2012 · VOL. 366 NO. 15. Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a public health challenge with an ...

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  8. www.sciencedirect.com › science › articleDengue virus infection – a review of pathogenesis, vaccines ...

    Jan 15, 2023 · The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human, causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar conserved structure and sequence among distinct DENV serotypes or different flaviviruses has resulted in the occurrence of cross reaction followed by antibody-dependent enhancement (ADE).

  9. ghc.fiu.edu › publications › perez_et_al-2019-tropThe decline of dengue in the Americas in 2017: discussion of ...

    Abstract. objective Since the 1980s, dengue incidence has increased 30-fold. However, in 2017, there was a noticeable reduction in reported dengue incidence cases within the Americas, including severe and fatal cases. Understanding the mechanism underlying dengue’s incidence and decline in the Americas is vital for public health planning.