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  1. Nov 24, 2020 · There are four serotypes of dengue virus which are antigenically distinct namely DENV-1, DENV-2, DENV-3, and DENV-4 . A fifth serotype (DENV-5) has been detected using isolation and genetic sequence analysis in Sarawak state of Malaysia in October 2013 . The incubation period of dengue virus infection is 4–7 days.

  2. Dec 15, 2021 · About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus infection is especially transmitted through bites of Aedes mosquitos, hugely spread in tropical and subtropical environments, mostly found in urban and semiurban areas. Unfortunately, there is no ...

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.
  3. May 1, 2024 · Dengue is the most rapidly emerging climate-sensitive infection, and there has been a 10-fold rise in cases over the past 20 years. Severe illness is characterized by vascular leakage, organ dysfunction, and severe bleeding which occur due to the direct effects of the viral non-structural protein NS1 and an aberrant host immune response.

  4. Oct 31, 2019 · Dengue fever may be caused by four different serotypes: DENV1, DENV2, DENV3, or DENV4 (Kostyuchenko et al., 2013), where the immunity towards the infecting serotype is life-long; however, severe forms of the disease may occur after the second or subsequent infection caused by a different dengue virus serotype, since the cross-protection against ...

    • Anny Karely Rodriguez, Ana Luisa Muñoz, Nidya Alexandra Segura, Héctor Rafael Rangel, Felio Bello
    • 10.17179/excli2019-1825
    • 2019
    • EXCLI J. 2019; 18: 988-1006.
  5. Aug 18, 2016 · Dengue is widespread throughout the tropics and local spatial variation in dengue virus transmission is strongly influenced by rainfall, temperature, urbanization and distribution of the principal ...

    • Maria G. Guzman
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  7. Apr 12, 2012 · DOI: 10.1056/NEJMra1110265. VOL. 366 NO. 15. Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a ...

  8. Jan 9, 2019 · Assuming that 20–40% of Zika or chikungunya cases were misclassified as dengue in 2015 and 2016, the decline in dengue would not have been as abrupt in 2017. Therefore, the group agreed that part of the decline in dengue incidence during 2017 resulted from over-reporting between 2015 and 2016.