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Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.
Apr 12, 2012 · There are an estimated 50 million infections per year with the dengue virus, which is transmitted primarily by urban-adapted Aedes aegypti mosquitoes. This review summarizes pathophysiology and tre...
Dec 15, 2021 · Unfortunately, there is no particular therapeutic approach, but prevention, adequate consciousness, detection at earlier stage of viral infection, and appropriate medical care can lower the fatality rates. This review offers a comprehensive view of production, transmission, pathogenesis, and control measures of the dengue virus and its vectors.
- 10.1155/2021/4224816
- 2021
- Biomed Res Int. 2021; 2021: 4224816.
Sep 20, 2019 · In this chapter we will discuss the evolution of virus and its vector, epidemiology of dengue, molecular and genomic structure of DENV, their pathogenesis, immune response of the host to the infection, laboratory diagnosis, management, and recent developments in dengue drug and vaccine development.
- Amudhan Murugesan, Mythreyee Manoharan
- 2020
- 10.1016/B978-0-12-819400-3.00016-8
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What is the pathogenesis of dengue?
What is the pathophysiology of dengue virus infection (DHF/DSS)?
What causes severe manifestations of dengue virus disease?
Apr 24, 2018 · Dengue virus (DENV), an arbovirus transmitted by mosquitoes, has become a major threat to American human life, reaching approximately 23 million cases from 1980 to 2017. Brazil is among the countries most affected by this terrible viral disease, with 13.6 million cases.
- Tiago Souza Salles, Thayane da Encarnação Sá-Guimarães, Evelyn Seam Lima de Alvarenga, Victor Guimar...
- 2018
Jan 15, 2023 · The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human, causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar conserved structure and sequence among distinct DENV serotypes or different flaviviruses has resulted in the occurrence of cross reaction followed by antibody-dependent enhancement (ADE). Thus far, the vaccine which can ...
Jan 24, 2019 · Here, we contrast the mechanisms initiating and sustaining adaptive immune responses during primary infection with the immune pathways that are pre-existing and reactivated during secondary dengue.
