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Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.
Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...
- 10.1155/2021/4224816
- 2021
- Biomed Res Int. 2021; 2021: 4224816.
Apr 22, 2024 · Dengue virus infection is known to induce endoplasmic reticulum (ER) stress, triggering signaling pathways associated with ER stress during viral infections. These pathways activate genes that support cell survival and anti-viral defenses.
This chapter provides an overview of the key areas of preparedness planning, epidemic detection and emergency response for dengue containment and control in endemic countries. It gives guidance to countries at risk of dengue introduction through the movement of infected persons or vectors.
- 2009
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Nov 19, 2023 · It was observed that PAIgG-coated platelets go through increased clearance via Fcγ receptors expressed on mononuclear phagocytic cells. The mechanism of action of IVIGs involves the ligation of inhibitory receptors or competitive suppression of Fcγ receptors.
Jan 15, 2023 · Abstract. The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human, causes illness ranging from mild dengue fever to fatal dengue shock syndrome.
May 1, 2024 · We discuss the molecular mechanisms of dengue pathogenesis, the gaps in our knowledge, and recent advances, as well as the most crucial questions to be answered to enable the development of therapeutics, biomarkers, and vaccines.
