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1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · Dengue virus genome encodes for three structural proteins (C, prM (M), and E) and seven non-structural (NS) proteins (NS1, NS2a, NS2B, NS3, NS4a, NS4B, and NS5). The most important non-structural protein which has been implicated in the pathogenesis of dengue viral infections is NS1 .

   • Figure - PMC - National Center for Biotechnology Information

     The pathogenesis of dengue virus infection is attributed to...

   • Molecular mechanism of pathogenesis of dengue virus: Entry ...

     Dengue fever is one of the major health problems in India....

2. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

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   Apr 22, 2024 · Dengue virus infection is known to induce endoplasmic reticulum (ER) stress, triggering signaling pathways associated with ER stress during viral infections. These pathways activate genes that support cell survival and anti-viral defenses.

3. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

   • DOI: 10.1155/2021/4224816
   • Published: 2021

   • Publication: Biomed Res Int. 2021; 2021: 4224816.

4. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

   www.sciencedirect.com › science › article

   May 1, 2024 · Dengue virus (DENV) can lead to mitochondrial dysfunction owing to excessive oxidative stress, and the NS2B3 protease complex of the virus modulates regulatory pathways leading to a further increase in oxidative stress.

5. People also ask

   How does a dengue virus interact with the host cellular machinery?

   • During dengue infection, the virus interacts with the host cellular machinery responsible for 5’ capping. DENV employs multiple strategies to hijack and manipulate this process. For instance, the virus sequesters essential host factors involved in capping, such as the cap-binding complex and associated enzymes.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   What is the pathogenesis of dengue?

   • The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What factors are involved in the pathogenesis of dengue virus infection?

   • 1. Summary of various factors implicated in pathogenesis of dengue virus infection Higher viremia levels of DENV-2 and DENV-3 in secondary infections. Inhibits antiviral genes and enhancing the production of IL-10. Apart from various viral factors implicated in the pathogenesis of DENV infection, host genetic factors also play an important role.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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6. www.sciencedirect.com › science › articleDengue virus infection – a review of pathogenesis, vaccines ...

   www.sciencedirect.com › science › article

   Jan 15, 2023 · Human normally gets infected by dengue virus (DENV) through infected mosquitoes such as Aedes aegypti or Aedes albopictus (Bhatt et al., 2013). DENV will target on the dendritic cells (DCs) and macrophages during first day of infection (Kyle et al., 2007).

7. www.nature.com › articles › nri3916New insights into the immunopathology and control of dengue ...

   www.nature.com › articles › nri3916

   Dengue virus is a relatively simple positive-sense single-stranded RNA virus that is 50 nm in diameter and has three structural proteins — capsid (C) protein, precursor membrane (prM) protein...