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1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

2. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

   • DOI: 10.1155/2021/4224816
   • Published: 2021

   • Publication: Biomed Res Int. 2021; 2021: 4224816.

3. link.springer.com › content › pdfCurrent Understanding of the Pathogenesis of Dengue Virus ...

   link.springer.com › content › pdf

   The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

   • File Size: 1MB
   • Author: Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...

   • Page Count: 16
   • Publish Year: 2021

4. www.nature.com › articles › nri3916New insights into the immunopathology and control of dengue ...

   www.nature.com › articles › nri3916

   This Review outlines recent advances in the understanding of immunopathology, vaccine development and human monoclonal antibodies produced against dengue virus. Aedes mosquito vector. The genus...

   • Author: Gavin Screaton, Juthathip Mongkolsapaya, Juthathip Mongkolsapaya, Sophie Yacoub, Sophie Yacoub, Cath...

   • Publish Year: 2015

5. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

   www.sciencedirect.com › science › article

   May 1, 2024 · We discuss the molecular mechanisms of dengue pathogenesis, the gaps in our knowledge, and recent advances, as well as the most crucial questions to be answered to enable the development of therapeutics, biomarkers, and vaccines.

6. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

   • Cached

   Apr 22, 2024 · Dengue virus infection is known to induce endoplasmic reticulum (ER) stress, triggering signaling pathways associated with ER stress during viral infections. These pathways activate genes that support cell survival and anti-viral defenses.

7. People also ask

   How does a dengue virus interact with the host cellular machinery?

   • During dengue infection, the virus interacts with the host cellular machinery responsible for 5’ capping. DENV employs multiple strategies to hijack and manipulate this process. For instance, the virus sequesters essential host factors involved in capping, such as the cap-binding complex and associated enzymes.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   What is the pathogenesis of dengue?

   • The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What is the pathophysiology of dengue virus infection (DHF/DSS)?

   • The pathogenesis of dengue virus infection and severe dengue manifestations is very complex and not completely understood. The pathophysiological hallmark of DHF/DSS is plasma leakage and deranged hemostasis.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

   See all results for this question

8. www.nature.com › articles › s41577/019/0123-xAdaptive immune responses to primary and secondary dengue ...

   www.nature.com › articles › s41577/019/0123-x

   Jan 24, 2019 · The existence of four different serotypes of dengue virus poses a challenge to vaccine development, as pre-existing immunity can lead to severe disease during infection with a heterologous...