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  1. Nov 24, 2020 · The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

  2. The dengue virus attaches to the surface of a host cell and enters the cell by a process called endocytosis. Once deep inside the cell, the virus fuses with the endosomal membrane and is...

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  4. May 1, 2024 · We discuss the molecular mechanisms of dengue pathogenesis, the gaps in our knowledge, and recent advances, as well as the most crucial questions to be answered to enable the development of therapeutics, biomarkers, and vaccines.

  5. en.wikipedia.org › wiki › Dengue_virusDengue virus - Wikipedia

    Dengue virus is transmitted by the mosquito species Aedes aegypti, which produces saliva that contains over 100 unique proteins, including the protein family D7. Scientists used to believe that A. aegypti saliva, when being transmitted, actually enhanced dengue virus in the body.

  6. Aug 18, 2016 · Four main factors control dengue virus (DENV) disease response along a response continuum: immune status, virus strain, genetic status and age. Individuals at risk of a secondary infection...

    • Maria G. Guzman
  7. Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions.

  8. Jan 15, 2023 · Introduction. Dengue virus infection is one of the most common mosquito-borne diseases occurring in both tropical and subtropical regions which causes up to about 100 to 400 million infected cases per year globally ( WHO, 2021 ).

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