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1. www.nature.com › scitable › topicpageDengue Viruses | Learn Science at Scitable - Nature

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   Introduction. Viruses are tiny agents that can infect a variety of living organisms, including bacteria, plants, and animals. Like other viruses, the dengue virus is a...

2. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

   • Author: Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
   • DOI: 10.1007/s00284-020-02284-w

   • Publish Year: 2021
   • Publication: Curr Microbiol. 2021; 78(1): 17-32.

3. People also ask

   What is the pathogenesis of dengue?

   • The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What is a dengue virus (DENV)?

   • Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   How does a dengue virus internalize?

   • D Envelope glycoproteins attach to host receptors and form the dengue-host membrane complex, resulting in virus internalization to process its replication and propagation inside the host cell [ 13] Humans and mosquitoes are the primary hosts and vectors of DENV, respectively.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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4. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

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   Apr 22, 2024 · Abstract. Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species.

5. www.nejm.org › doi › fullDengue | New England Journal of Medicine

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   Apr 12, 2012 · Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a public health challenge with...

6. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

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   May 1, 2024 · Bleeding following dengue virus infection occurs due to multiple mechanisms including platelet activation by NS1, serotonin, and PAF, accompanied by a wide range of other coagulation abnormalities.

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8. www.sciencedirect.com › science › articleDengue virus infection – a review of pathogenesis, vaccines ...

   www.sciencedirect.com › science › article

   Jan 15, 2023 · The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human, causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar conserved structure and sequence among distinct DENV serotypes or different flaviviruses has resulted in the occurrence of cross reaction followed by antibody-dependent ...

9. journals.sagepub.com › doi › 10Dengue Virus: Molecular Biology and Recent Developments in ...

   journals.sagepub.com › doi › 10

   Nov 19, 2023 · The Life Cycle of Dengue Virus. (Dengue virus enters the host by receptor-mediated endocytosis, which subsequently results in the fusion of vesicular and viral membranes. This fusion allows the secretion of genomic RNA into the cytoplasm, which plays a role as mRNA for replication and translation.