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Nov 24, 2020 · The dengue virus nonstructural-1 protein (NS1) generates antibodies to common epitopes on human blood clotting, integrin/adhesin proteins and binds to human endothelial cells: potential implications in haemorrhagic fever pathogenesis.
Jun 13, 2019 · In humans, DENV infection causes dengue fever (DF) and in severe cases, dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). In the transmission cycle, upon injection into the human body, the virus gains entry into the host’s cells, hijacks the host’s cell machinery to replicate, and escapes the host’s immune strategies to ...
Oct 25, 2010 · Each year, the virus infects up to 100 million people and kills about 22,000, most of them children. To infect a cell, the dengue virus initially binds to the cell surface. It gains entry into the cell when it becomes enveloped by the cell membrane during the creation of a pouch-like structure known as an endosome.
Sep 20, 2019 · These counteracting mechanisms allow the virus to establish infection in humans and possibly affect the generation of effective adaptive immune responses that are initiated and regulated by DCs. Moreover, some of the elements involved in antiviral innate immune responses are targeted by DENV .
Jan 24, 2019 · Abstract. Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the circulation of multiple serotypes, global expansion of the disease and recent gains in...
Aug 18, 2016 · Four main factors control dengue virus (DENV) disease response along a response continuum: immune status, virus strain, genetic status and age. Individuals at risk of a secondary...
Introduction. Viruses are tiny agents that can infect a variety of living organisms, including bacteria, plants, and animals. Like other viruses, the dengue virus is a microscopic structure...
