Yahoo Web Search

Search results

  1. Jul 2, 2021 · This narrative review aims to present the varied manifestations, postulated mechanisms, and the available treatment options for psychiatric morbidity associated with dengue. The evidence available from eight observational studies is summarized in this review.

  2. Nov 24, 2020 · The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

    • Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
    • 10.1007/s00284-020-02284-w
    • 2021
    • Curr Microbiol. 2021; 78(1): 17-32.
  3. Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.
  4. The dengue virus nonstructural-1 protein (NS1) generates antibodies to common epitopes on human blood clotting, integrin/adhesin proteins and binds to human endothelial cells: potential implications in haemorrhagic fever pathogenesis.

    • Byron E. E. Martina, Penelope Koraka, Albert D. M. E. Osterhaus
    • 10.1128/CMR.00035-09
    • 2009
    • Clin Microbiol Rev. 2009 Oct; 22(4): 564-581.
  5. Jan 15, 2023 · Human normally gets infected by dengue virus (DENV) through infected mosquitoes such as Aedes aegypti or Aedes albopictus (Bhatt et al., 2013). DENV will target on the dendritic cells (DCs) and macrophages during first day of infection (Kyle et al., 2007).

  6. May 1, 2024 · In this review we discuss the molecular mechanisms of dengue pathogenesis and highlight recent developments and gaps in our knowledge which are important for the identification of dengue biomarkers and drug targets.

  7. Dengue virus (DENV) can lead to mitochondrial dysfunction owing to excessive oxidative stress, and the NS2B3 protease complex of the virus modulates regulatory pathways leading to a further increase in oxidative stress.