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1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

   • Figure - PMC - National Center for Biotechnology Information

     The pathogenesis of dengue virus infection is attributed to...

   • Dengue Virus Pathogenesis: an Integrated View - PMC

     His studies focused on virus outbreaks in wildlife,...

   • Dengue virus: epidemiology, biology, and disease aetiology

     Dengue is a vector-borne viral disease caused by the...

2. www.nature.com › articles › nrdp201655Dengue infection | Nature Reviews Disease Primers

   www.nature.com › articles › nrdp201655

   Aug 18, 2016 · This Primer provides a general overview on dengue, covering epidemiology, control, disease mechanisms, diagnosis, treatment and research priorities. Infection with any one of the four dengue virus ...

   • Author: Maria G. Guzman

3. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

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   Apr 22, 2024 · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...

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5. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

   www.sciencedirect.com › science › article

   May 1, 2024 · Therefore, although ADE is important in dengue disease pathogenesis, its specificity and functionality of DENV-specific antibodies appear to play a role. In ADE, poorly neutralizing and highly crossreactive antibodies enhance infection in FcγR-expressing cells, thereby increasing the intracellular viral loads (Figure 1) [42., 43., 44.].

6. pubs.acs.org › doi › pdfOverview of Pathogenesis, Diagnostics, and Therapeutics of ...

   pubs.acs.org › doi › pdf

   viral diseases caused by dengue and Zika. 1. INTRODUCTION Several arthropod-borne viruses (arboviruses) have been identified to date, and many of them are known to cause infections in humans.1 An outbreak of epidemics triggered by the reemergence of infective viruses causing dengue (DENV), Zika (ZIKV), and chikungunya (CHIKV) demands develop-