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   What causes severe manifestations of dengue virus disease?

   • The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What are the signs and symptoms of dengue fever?

   • Dengue fever causes a high fever — 104 F (40 C) — and any of the following signs and symptoms: Most people recover within a week or so. In some cases, symptoms worsen and can become life-threatening. This is called severe dengue, dengue hemorrhagic fever or dengue shock syndrome.

   Dengue fever - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/dengue-fever/symptoms-causes/syc-20353078

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   What is the pathogenesis of dengue?

   • The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

   See all results for this question

2. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

   • Figure - PMC - National Center for Biotechnology Information

     The pathogenesis of dengue virus infection is attributed to...

   • Dengue Fever - StatPearls - NCBI Bookshelf

     This disease is also known by various monikers, such as...

3. www.mayoclinic.org › diseases-conditions › dengueDengue fever - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › dengue

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   Oct 5, 2022 · Overview. Dengue (DENG-gey) fever is a mosquito-borne illness that occurs in tropical and subtropical areas of the world. Mild dengue fever causes a high fever and flu-like symptoms. The severe form of dengue fever, also called dengue hemorrhagic fever, can cause serious bleeding, a sudden drop in blood pressure (shock) and death.

4. my.clevelandclinic.org › health › diseasesDengue Fever: Causes, Symptoms & Treatment - Cleveland Clinic

   my.clevelandclinic.org › health › diseases

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   Jun 6, 2022 · This includes abdominal pain, blood in your vomit or poop, bleeding gums or nose, frequent vomiting or extreme tiredness or restlessness. What is dengue fever? Dengue fever is an illness you can get from the bite of a mosquito carrying one of four types of dengue virus (DENV).

5. www.nejm.org › doi › fullDengue | New England Journal of Medicine

   www.nejm.org › doi › full

   Apr 12, 2012 · Although most dengue virus infections are asymptomatic, a wide variety of clinical manifestations may occur, ranging from mild febrile illness to severe and fatal disease. 1 The differential...

6. www.who.int › news-room › fact-sheetsDengue and severe dengue - World Health Organization (WHO)

   www.who.int › news-room › fact-sheets

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   Apr 23, 2024 · Symptoms. Most people with dengue have mild or no symptoms and will get better in 1–2 weeks. Rarely, dengue can be severe and lead to death. If symptoms occur, they usually begin 4–10 days after infection and last for 2–7 days. Symptoms may include: high fever (40°C/104°F) severe headache. pain behind the eyes. muscle and joint pains. nausea.

7. en.wikipedia.org › wiki › Dengue_virusDengue virus - Wikipedia

   en.wikipedia.org › wiki › Dengue_virus

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   A recent systematic review and meta-analysis showed that allergic symptoms are one of the core symptoms that are highly associated with dengue severity. Mechanism of infection. Dengue virus' (DENV) E envelope protein binds to a cellular receptor. The exact nature of the cellular receptor has not been fully elucidated.