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1. • • Dengue virus (DENV) has evolved various strategies to manipulate the innate immune responses of the host such as ‘hiding’ in the ultrastructure of the host, interfering with the signaling pathway through RNA modifications, inhibiting type 1 IFN production, as well as inhibiting STAT1 phosphorylation.
     www.ncbi.nlm.nih.gov › pmc › articles

     Innate and adaptive immune evasion by dengue virus - PMC

2. People also ask

   What is the innate antiviral response to dengue virus (DENV)?

   • The innate antiviral response to dengue virus (DENV) is implemented by a variety of immune cells and inflammatory mediators. If these components are in balance, viral clearance is efficient and, consequently, infections will be asymptomatic or will only have mild clinical manifestations.

   Innate Immune Response to Dengue Virus: Toll-like Receptors and

   www.ncbi.nlm.nih.gov/pmc/articles/PMC9147118/

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   How does dengue virus affect the body?

   • Dengue virus causes a range of diseases with a small proportion of infected patients developing severe plasma leakage that leads to dengue shock syndrome, organ impairment and bleeding. Infection with one of the four viral serotypes results in the development of homotypic immunity to that serotype.

   New insights into the immunopathology and control of dengue virus

   www.nature.com/articles/nri3916

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   What factors affect the clinical outcome of dengue?

   • Viral and host factors are related to the clinical outcome of dengue, although the disease pathogenesis remains uncertain. The innate antiviral response to DENV is implemented by a variety of immune cells and inflammatory mediators. Blood monocytes, dendritic cells (DCs) and tissue macrophages are the main target cells of DENV infection.

   Innate Immune Response to Dengue Virus: Toll-like Receptors and

   www.ncbi.nlm.nih.gov/pmc/articles/PMC9147118/

   See all results for this question

3. www.ncbi.nlm.nih.gov › pmc › articlesDengue virus and the host innate immune response - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Oct 10, 2018 · The innate immune response to DENV is not well characterized nor are the exact roles of the NS proteins in evading the immune response. The main innate immune response is type I IFN and the main evasion mechanism of the virus is to target against the type I IFN response.

   • Innate Immune Response to Dengue Virus: Toll-like Receptors ...

     The innate antiviral response to dengue virus (DENV) is...

   • Innate and adaptive immune evasion by dengue virus - PMC

     The innate immune system acts as the first line of defense...

4. www.nature.com › articles › s41577/019/0123-xAdaptive immune responses to primary and secondary dengue ...

   www.nature.com › articles › s41577/019/0123-x

   Jan 24, 2019 · Abstract. Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the circulation of multiple serotypes, global expansion of the disease and recent gains in vaccination...

   • Author: Ashley L St John, Ashley L St John, Abhay P S Rathore

   • Publish Year: 2019

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6. www.nature.com › scitable › topicpageHost Response to the Dengue Virus | Learn Science at Scitable

   www.nature.com › scitable › topicpage

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   The immune system is the body's primary defense against the dengue virus. When someone is infected with dengue, the innate and adaptive immune responses combine forces to fight the virus.

7. www.tandfonline.com › doi › fullFull article: Dengue virus and the host innate immune response

   www.tandfonline.com › doi › full

   Oct 10, 2018 · The innate immune response to DENV is not well characterized nor are the exact roles of the NS proteins in evading the immune response. The main innate immune response is type I IFN and the main evasion mechanism of the virus is to target against the type I IFN response.

8. www.nature.com › articles › nri3916New insights into the immunopathology and control of dengue ...

   www.nature.com › articles › nri3916

   Nov 25, 2015 · Metrics. Key Points. Dengue virus has four distinct serotypes, and infection with one serotype results in the development of homotypic immunity. Subsequent infection with a different serotype...