Search results
- Fish oil, ginseng, and saw palmetto are not associated with bleeding.
www.ncbi.nlm.nih.gov › pmc › articlesDietary supplements and bleeding - PMC - National Center for ...
People also ask
What are the side effects of saw palmetto?
Does saw palmetto cause liver damage?
How does saw palmetto affect pregnancy?
Apr 15, 2024 · Large-scale studies funded by the National Institutes of Health (NIH) during the past two decades found that saw palmetto was no more effective in treating BPH than a placebo (or fake treatment). Other reviews reached similar conclusions. There also is no clear evidence showing that saw palmetto is beneficial in addressing:
- Overview
- What is saw palmetto?
- May benefit prostate health and urinary function
- May reduce male pattern baldness
- Other potential benefits
- Safety and side effects
- Potentially effective dosages
- The bottom line
Saw palmetto may provide health benefits, including supporting prostate and urinary health and reducing male pattern baldness. It may have additional uses, though more research is needed.
Saw palmetto is a supplement made from the fruit of the Serenoa repens tree.
It’s often used to treat enlarged prostate, improve urinary function, and enhance hair growth. Some also use the supplement to boost libido and fertility and reduce inflammation. Finally, saw palmetto is claimed to have anticancer effects.
However, not all of its uses and purported health benefits are supported by science.
Saw palmetto, or Serenoa repens, is a dwarf palm tree native to the southeast regions of North America and especially abundant in Florida, Georgia, Cuba, and the Bahamas (1).
It grows in sandy soil and gets its name from the sharp, saw-like teeth on the stalks that attach the tree’s leaves to its stem. The saw palmetto tree produces dark berries that contain a large seed (1).
The saw palmetto fruit has long been used by Native Americans for its nutritional, diuretic, sedative, aphrodisiac, and cough-reducing properties.
Nowadays, the berries are eaten whole or dried and used to make tea. Dried and ground saw palmetto can also be purchased in capsule or tablet form. It’s widely available, including online.
Still, the most common form on the market is oily extracts of the fatty portions of the dried berries (1).
These supplements contain 75–90% fats depending on the extraction method. They typically provide higher amounts of beneficial plant compounds like vitamin E and other antioxidants compared to the raw fruit (2).
Saw palmetto may help treat benign prostatic hyperplasia (BPH) — a medical condition characterized by a slow, noncancerous yet abnormal enlargement of the prostate.
BPH is common in older men, affecting up to 75% of men in their 70s (3).
If left untreated, the prostate can enlarge to the point of interfering with the ability to properly empty the bladder. It can also increase the frequency and urge to urinate, often causing excessive nighttime urination which may disrupt sleep.
BPH is part of a larger group of lower urinary tract symptoms (LUTS), a group of symptoms typically involving the bladder, urethra, and prostate. Unlike BPH, LUTS can affect both men and women (4, 5).
Several studies have looked at saw palmetto’s effect on LUTS — with mixed results.
Early studies reported that saw palmetto may help increase urine flow and reduce nighttime urination in men with BPH — both when used alone or in combination with traditional drug therapy (6, 7, 8, 9, 10).
Saw palmetto may help prevent androgenic alopecia — a type of hair loss also known as male and female pattern baldness in men and women, respectively.
It’s thought to work by blocking the enzyme that converts testosterone to dihydrotestosterone (DHT), an androgen-type hormone believed to cause this form of hair loss (14, 15).
Higher levels of androgen hormones like DHT are thought to shorten the hair growth cycle and lead to the growth of shorter and thinner strands of hair (15).
One small study reports that a daily 200-mg dose of saw palmetto — taken with another beneficial plant compound known as beta-sitosterol — reduced hair loss in 60% of men with androgenic alopecia compared to a placebo (16).
In a 2-year study, men with male pattern baldness were given 320 mg of saw palmetto per day or finasteride, a conventional hair loss medication.
By the end of the study, about one-third of those given saw palmetto reported an increase in hair growth. That said, saw palmetto was only half as effective as the conventional medication (17).
Saw palmetto is touted as providing additional benefits — though most are unsupported by strong science.
For instance, test-tube research shows that Permixon – a specific formulation of saw palmetto – may reduce markers of inflammation in prostate cells. However, it’s unclear whether other saw palmetto supplements have the same effect (19, 20).
Permixon may also protect libido and fertility in men. Conventional drug therapy for BPH and LUTS has been shown to negatively impact sexual function in men.
A review of 12 randomized controlled studies — the gold standard in nutrition research — compared Permixon with conventional drug therapy as a treatment for BPH and LUTS.
Though both produced negative side effects on male sexual function, the saw palmetto supplement led to smaller drops in libido and lower impotence compared to the conventional drug treatment (12).
Still, it’s unclear whether Permixon has the same effect in healthy men or whether other saw palmetto formulations offer similar protective benefits.
Though raw and dried saw palmetto berries have been eaten for centuries, their safety hasn’t been directly studied.
That said, studies suggest that saw palmetto supplements are generally safe for most people. The most common side effects include diarrhea, headache, fatigue, decreased libido, nausea, vomiting, and vertigo. Yet, they tend to be mild and reversible (21).
More serious side effects like liver damage, pancreatitis, bleeding in the brain, and death have been reported in isolated cases. However, it isn’t always clear whether saw palmetto was the cause (21, 25, 26, 27).
Two case studies further report that young girls experienced hot flashes when given saw palmetto supplements to treat hair loss or hirsutism — a condition causing unwanted male-pattern hair growth in women (28, 29).
Moreover, there is some concern that saw palmetto may be linked to birth defects and may prevent the normal development of male genitalia (1).
Therefore, use is strongly discouraged in children, as well as pregnant or breastfeeding women.
Saw palmetto can be taken in many forms.
Little research exists on effective dosages when the saw palmetto berries are eaten whole or steeped to make a tea.
When taken as a dried supplement or an oily liquid extraction, saw palmetto appears most effective in daily dosages of 160–320 mg (12, 13, 16, 17).
That said, most studies have been done exclusively in men, so it’s unclear whether the same dosages are appropriate for women (1).
Always consult your healthcare provider before taking saw palmetto to ensure your safety and appropriate dosage.
Summary
Saw palmetto is a supplement made from the fruit of the Serenoa repens tree.
It may offer health benefits like improved hair growth, prostate health, and urinary function.
According to test-tube studies, it may also have anti-inflammatory and anticancer properties, but more research in these areas is needed.
It’s best to discuss this supplement with your healthcare provider before giving it a try. Children and pregnant or breastfeeding women should abstain from taking saw palmetto.
Oct 16, 2023 · You are taking warfarin or other blood thinners: Saw palmetto may increase the risk of bruising and bleeding. You are taking antiplatelets such as clopidogrel: Saw palmetto may increase the effects of these drugs. You are taking nonsteroidal anti-inflammatory drugs (NSAIDs): Saw palmetto may increase the side effects of these drugs.
Oct 7, 2022 · Saw palmetto can also increase the risk of bleeding by affecting the body’s blooding-clotting ability and interfering with the activity of blood thinners like warfarin and coumadin. Saw palmetto may also impact the absorption of iron by the body.
Sep 15, 2022 · Fish oil, ginseng, and saw palmetto are not associated with bleeding. Evidence for overall bleeding risk associated with St. John’s wort, ginger, ginkgo biloba, or cranberry supplementation is conflicting. In conclusion, physicians must be aware of the potential anticoagulant effects of these supplements.
- 10.1080/08998280.2022.2121575
- 2022
Sep 16, 2021 · However, while it's considered a very safe supplement, saw palmetto can interact with certain anti-platelet drugs and anticoagulants such as aspirin or warfarin, per University of Michigan Health. Saw palmetto can also increase the side effects of NSAIDs, including liver damage, per Memorial Sloan Kettering Cancer Center. Pregnant and ...
Saw palmetto may increase the risk of bruising and bleeding. You are taking antiplatelets such as clopidogrel: Saw palmetto may increase the effects of these drugs.
