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      • Avoid taking an anti-diarrheal medication — this slows your digestive system down, preventing your body from getting rid of the toxins. Antibiotics generally aren't recommended because they can increase the risk of serious complications and they don't appear to help treat the infection.
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  2. Feb 13, 2024 · To ensure treatment with an effective antibiotic, many patients with septic shock suspected to be due to gram-negative organisms may require initial therapy with two antimicrobials from two different classes (ie, combination therapy), although this practice depends upon the organisms that are considered likely pathogens and local antibiotic ...

  3. Aug 26, 2021 · Using a 90% minimum threshold, for infections like VAP and CLABSI, we will potentially need to recommend toxic (e.g., aminoglycoside), reserved (e.g., carbapenem), or toxic and reserved (e.g., colistin) combinations of antibiotics for almost every patient, further driving antibiotic resistance.

    • Michael S. Niederman, Rebecca M. Baron, Lila Bouadma, Thierry Calandra, Nick Daneman, Jan DeWaele, M...
    • 10.1186/s13054-021-03736-w
    • 2021
    • Crit Care. 2021; 25: 307.
  4. Aug 8, 2020 · Antibiotics are often given as a single dose in the ED, but using symptom-based treatment pathways or sepsis protocols and order-sets with scheduled antibiotics beyond the initial dose can (1) ensure that subsequent doses are given and (2) provide standardization to improve appropriateness of antibiotic selection . Other means of impacting ...

    • Jeffrey R Strich, Jeffrey R Strich, Emily L Heil, Henry Masur
    • 2020
  5. Severe Sepsis and Septic Shock Antibiotic Guide. Table 1: Antibiotic selection options for healthcare associated and/or immunocompromised patients. Healthcare associated: intravenous therapy, wound care, or intravenous chemotherapy within the prior 30 days, residence in a nursing home or other long-term care facility, hospitalization in an ...

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  6. The most current version of this IDSA guidance document and corresponding date of publication is available at: www.idsociety.org/practice-guideline/amr-guidance. Table 1. Suggested dosing of antibiotics for the treatment of antimicrobial resistant infections in adults, assuming normal renal and hepatic function.

  7. Apr 1, 2020 · The latest guidelines recommend starting antimicrobials within one hour, but this is controversial. Vasopressor therapy is indicated if hypotension persists despite fluid administration.

  8. Antimicrobial Stewardship disease state treatment guidelines should be utilized to select empiric antimicrobial therapy and to ensure appropriate dosing ( Table 1 ). (I-E) MRSA nasal swabs, when negative, can eliminate the need for MRSA coverage in sepsis patients.

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