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Oct 15, 2021 · Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented, single-stranded RNA that contains seven genes: (a) nucleoprotein (NP), (b) viral protein 35 (VP35), (c) VP40, (d) glycoprotein (GP), (e) VP30, (f) VP24, and (g) RNA polymerase (L).
- Sahil Jain, Sahil Jain, Ekaterina Martynova, Albert Rizvanov, Svetlana Khaiboullina, Manoj Baranwal
- 10.3390/pathogens10101330
- 2021
- Pathogens. 2021 Oct; 10(10): 1330.
Aug 10, 2022 · Learn about the morphology, genome, and proteins of Ebola Virus, a filovirus with a negative-sense RNA genome. See how the virus attaches to host cells and replicates using its glycoprotein spikes.
Structure. Ebolavirus is a filamentous, enveloped virus within the order Mononegavirales which also contains rabies and measles viruses. [15] . This order is characterized by non-segmented, single-stranded negative-sense RNA (-ssRNA) genomes that are surrounded by a helical nucleocapsid. [16] .
May 6, 2020 · Filoviruses replicate in the cytoplasm of their target cells. 16-18 Viral particles attach to the cell surface through the binding of glycoprotein to multiple attachment factors, such as C-type...
Sep 28, 2022 · Structural analysis revealed that Ebola virus L possesses a filovirus-specific insertion element that is essential for RNA synthesis, and that VP35 interacts extensively with the N-terminal...
Sep 1, 2016 · Ebola virus is a filamentous, enveloped virus containing a 19‐kb, negative‐strand RNA genome that encodes 7 genes and 9 proteins . At the genome ends, short, extragenic regions, called leader and trailer sequences, contain encapsidation signals as well as replication and transcription promoters.
Oct 17, 2018 · Our structure reveals how the Ebola virus nucleocapsid core encapsidates its viral genome, its sequence-independent coordination with RNA by nucleoprotein, and the dynamic transition between...
